ABSTRACT Mucosal surfaces are sites of highly dynamic interactions among epithelial and immune cells, environmental exposures, particularly dietary inputs, and the diverse microbial communities and their metabolites. These elements continually influence each other to maintain homeostasis and ensure appropriate immune discrimination between pathogens ...
Clara Delaroque +5 more
wiley +1 more source
Dendritic Cell α‐Ketoglutarate Regulates Tfh Polarization in Allergy
Allergen induces a dendritic cell metabolism shift toward glutaminolysis with α‐ketoglutarate as a regulator of Tfh subset polarization. Glutaminolysis is required for DC allergen uptake, co‐stimulatory molecule expression, and CLR expression. Modulation of glutaminolysis, JmjD3 histone demethylation, or HIF‐1α degradation alters Tfh polarization and ...
Anuj Tharakan +16 more
wiley +1 more source
Scalable electrochemical system for rapid on-site detection of food allergens. [PDF]
Cho YK +7 more
europepmc +1 more source
Role of Cysteinyl Leukotrienes in Food Allergy and Anaphylaxis: A Potential Therapeutic Target
Allergy, EarlyView.
Adrienn Weingärtner, Thomas Eiwegger
wiley +1 more source
Sensitization to food allergens is associated with more severe wheezing in children. [PDF]
Yılmaz O +7 more
europepmc +1 more source
Microbiota Signatures in Early Life and Their Association With Food Allergy: A Systematic Review
ABSTRACT Food allergy (FA) is increasing worldwide, and early life may be a critical window for immune training. We systematically reviewed observational human studies linking early‐life microbiota (infant, maternal, environmental, or extraintestinal) profiled using culture‐based and/or culture‐independent methods (including sequencing‐based approaches)
Eduard Flores Ventura +7 more
wiley +1 more source
"Allergolds": Gold Nanocluster-Based Bioconjugates of Food Allergens with Reduced Immunoglobulin E Binding. [PDF]
Martinez-Macias V +6 more
europepmc +1 more source
This study examines the current state of food allergy prevention guideline implementation worldwide, identifying key variables that may explain the observed global variation. Among 731 healthcare professionals across 80 countries, geography and clinical specialty independently drove allergenic food introduction practices, creating an 8.5‐month practice
Agnes Sze‐yin Leung +20 more
wiley +1 more source
Sensitization Patterns to Aeroallergens and Food Allergens Among Children with Atopic Asthma in Southwestern Saudi Arabia. [PDF]
Asseri AA +8 more
europepmc +1 more source
Route of Allergen Immunotherapy: A Global Look Into Physicians' Motivations
Little is known about the factors driving AIT prescription in clinical practice, including the level of personalization from patient to patient. Patient‐centred factors theoretically would favour SLIT prescription. Doctors’ knowledge, training, and country influence the final decision on the route.
Carmen Vidal +42 more
wiley +1 more source

