Results 201 to 210 of about 175,924 (305)

Localized NF‐κB Inhibition Reduces Lipid Nanoparticle‐Associated Inflammation

open access: yesAdvanced Science, EarlyView.
Lipid nanoparticles (LNPs) activate NF‐κB and provoke inflammation that limits therapeutic delivery. By encapsulating selective NF‐κB inhibitors within LNPs, localized suppression of inflammatory signaling is achieved without compromising mRNA expression.
Carolann L. Espy   +16 more
wiley   +1 more source

Promoting Dairy Consumption Among Families: Development and User Experience Study of a Web-Based Nutrition Intervention. [PDF]

open access: yesJMIR Form Res
Lemay J   +8 more
europepmc   +1 more source

Polymer Matrix‐Based 3D Culture Significantly Enhances the Differentiation and Immunomodulatory Functions of Human Adipose‐Derived Stem Cells

open access: yesAdvanced Science, EarlyView.
The 3D culture of human adipose‐derived stem cells (hADSCs) on a crosslinked cyclosiloxane‐based poly‐Z matrix platform enables the formation of spheroid structures enriched with extracellular matrix (ECM). These ECM‐enriched hADSC spheroids cultured on poly‐Z exhibit enhanced differentiation potential, immunomodulatory capacity, and in vivo ...
Changjin Seo   +6 more
wiley   +1 more source

Axial F–Bi–Ov Electron Pump Drives Continuous Reconfiguration of Bi Sites for Efficient Photocatalytic N2 Reduction

open access: yesAdvanced Science, EarlyView.
Axial Fluorine and Light‐Induced Oxygen Vacancies Synergize as an Electron Pump to Lower N2 Activation Energy and Enable Sustained NH3 Synthesis on FBWO. ABSTRACT The electronic structure precision of single‐atom catalysts (SACs) represents a decisive factor limiting advancements in photocatalytic nitrogen reduction (NRR) efficiency.
Xiao Ge   +6 more
wiley   +1 more source

An Implantable Scaffold Sequentially Releasing STING Agonist and B7‐H3 Antibody for Bone Metastasis Immunotherapy

open access: yesAdvanced Science, EarlyView.
We developed an implantable dual‐drug depot using GelMA for bone metastasis treatment, co‐delivering MSA‐2 and αB7‐H3‐loaded CaCO3 microparticles. Sustained release from GelMA scaffold enables MSA‐2 to activate STING signaling and enhance T‐cell infiltration and activation, while sequentially released αB7‐H3 blocks MSA‐2‐induced B7‐H3 upregulation ...
Qijun Lin   +10 more
wiley   +1 more source

Toxicity and Residual Effect of Toxic Baits on Adults of Spodoptera frugiperda (Lepidoptera: Noctuidae): Implications for Pest Management. [PDF]

open access: yesInsects
Silva Filho JGD   +13 more
europepmc   +1 more source

Catechol Derivative‐Based Bioadhesives: Molecular Design for Precision Medical Adhesion

open access: yesAdvanced Science, EarlyView.
This study utilizes tree‐inspired side‐chain engineering to graft five catechol derivatives onto PVA, systematically revealing how side‐chain length and substituents regulate adhesion and cohesion properties. Among them, the PVA‐CA patch demonstrates superior tissue adhesion, biocompatibility, and promotes regeneration, establishing a programmable ...
Xueyu Wang   +8 more
wiley   +1 more source

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