Challenges of vertical integration of supply chains' members of food and organic products with domestic origin [PDF]
Anali Ekonomskog fakulteta u Subotici, 2018 This research is focused on the possibility of applying the process of vertical cooperation and/or integration of members of the supply chain of products with domestic origin in the AP Vojvodina market so that create and preserve the long-term ...
Končar Jelena +2 more
doaj
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
FEBS Open Bio, EarlyView.BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
Key supply chain integration factors for success of medical device startups
, 2018 Thesis: M. Eng. in Supply Chain Management, Massachusetts Institute of Technology, Supply Chain Management Program, 2018.Cataloged from PDF version of thesis.Includes bibliographical references (pages 60-62).Healthcare cost are on the rise and becoming a
Gupta, Sanjay, M. Eng. Massachusetts Institute of Technology
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The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity
FEBS Open Bio, EarlyView.Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav +4 more
wiley +1 more source
Chain Management: All about Success [PDF]
Nowadays food products are produced in vertically collaborating networks. The questions of how such chain networks have to be designed and which governance structure fits best have been addressed in several well known articles. However, questions dealing
Gagalyuk, Taras, Hanf, Jon Henrich
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A critical analysis of supply chain integration in the agro-food industry [PDF]
, 2012 Supply chain integration has become the recent attention and debate in the supply chain management mainstream and literature. It also holds key elements to supply chain performances, through both internal and external integration.
KALCHSCHMIDT, Matteo Giacomo Maria +1 more
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MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation
FEBS Open Bio, EarlyView.MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima +8 more
wiley +1 more source
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
FEBS Open Bio, EarlyView.To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
FEBS Open Bio, EarlyView.Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
The Relationship between Supply Chain Coordination and Quality Assurance Systems: A Case Study Approach on the German Meat Sector [PDF]
The German meat industry faces a high demand for food safety and traceability. After several meat scandals in the recent past, efforts have to be made to regain consumer trust and to assure access to export markets.
Bahlmann, Jan, Spiller, Achim
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