Results 241 to 250 of about 8,677,306 (306)

Targeting the KAT7/H3K14ac/RAC2 Axis Mediates OXPHOS to Promote Stemness Maintenance and Malignancy in Glioblastoma

Advanced Science, EarlyView.
SOX2 upregulates KAT7 in glioma stem cells, where KAT7 deposits H3K14 acetylation at the RAC2 promoter to activate RAC2 transcription. RAC2‐GTP subsequently promotes PAK1/2/3 phosphorylation, increasing tricarboxylic acid cycle flux and mitochondrial respiration to support glioblastoma malignancy.
Jilong Liu, Yanfei Sun, Yuehua Zhu, Guangjing Mu, Jiazheng Wang, Liangliang Wang, Feihu Zhao, Zhimin Zhao, Jian Wang, Ying He, Zheng Jiang, Xingang Li, Mingzhi Han, Bin Huang   +13 more
wiley   +1 more source

Understanding the tradeoffs between quality and morality: Insights from consumer response to animal welfare eggs in China. [PDF]

Poult Sci
Zhang J, Liu Y, Wang J, Tan X.
europepmc   +1 more source

Abstract Representation of Movement Parameters in Basal Ganglia Output

Advanced Science, EarlyView.
The basal ganglia output provides a scalable velocity/position signal across behavioral contexts, supporting the idea that these variables are represented in the brain as abstract entities rather than as fixed changes in joint angles or specific sets of body effectors.
Ana Silvia Báez‐Cordero, Diana I. Ortega‐Romero, Claudia I. Pérez‐Díaz, Pavel E. Rueda‐Orozco   +3 more
wiley   +1 more source

Consumer Language-Based Sensory Descriptor Extraction and Volatile-Sensory Associations in Aged Light Flavor Baijiu. [PDF]

J Food Sci
Liao S, Wang X, Han H, Meng T, Song J, Zhang Y, Han Y, Wang B.   +7 more
europepmc   +1 more source

Hierarchical Flux‐Protection Engineering Stabilizes Oxidation‐Prone Metabolic Nodes for High‐Level Curcumin Biosynthesis

Advanced Science, EarlyView.
Flux‐protection engineering stabilizes an oxidation‐prone L‐DOPA node in engineered E. coli by combining acid‐adapted chassis evolution, respiratory‐chain modulation, enzyme‐level flux matching, and pH–DO control. Carbon is redirected from oxidative browning to productive biosynthesis, enabling 1075.2 mg/L curcumin and demonstrating transferability to ...
Jianbin Chen, Qihang Chen, Shurong Zhang, Yajuan Su, Xiaoyi Zou, Ke Wang, Shike Liu, Qian He, Liang Zhang, Weizhu Zeng, Jingwen Zhou   +10 more
wiley   +1 more source

When giant amphibians rule the river: Community trophic structure of Japanese giant salamander ecosystems. [PDF]

Ecology
Duret C, Lejeune B, Lepoint G, Bartet T, Okada S, Fukushima K, Kishida O, Denoël M.   +7 more
europepmc   +1 more source

Valorization of Wheat Milling Co-Products in <i>Carasau</i> Bread: Effects of Their Addition as Powders or After Fermentation on Physicochemical Properties, Volatile Profile and Sensory Characteristics. [PDF]

Foods
Sanna M, Tolu V, Fois S, Serra M, Piu PP, Piras D, Sanna V, Loddo A, Roggio T, Catzeddu P.   +9 more
europepmc   +1 more source