Results 51 to 60 of about 2,171,577 (311)

Carbohydrate (CHO) Intake and Quality during Adolescence and Association with HOMA2-IR in Adulthood—The Role of the Chronotype

open access: yesProceedings
Background/objectives: Adolescence is associated with two risk markers of Type 2 Diabetes Mellitus (T2DM): insulin resistance and lateness in chronotype. Hence, negative eating behavior during adolescence may increase the future risk of T2DM.
Nicole Jankovic   +6 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

El consumo alimenticio de la élite hidalga en Galicia durante el siglo XVIII [PDF]

open access: yesHistoria. Instituciones. Documentos, 2012
During the 18th century, the Galician noble elite experienced a magnificent period that was evident in a higher investment in the luxury market relative to the previous centuries. One of their most significant luxury expenses was food.
Antonio Presedo Garazo
doaj  

Is Meat the New Tobacco? Regulating Food Demand in the Age of Climate Change [PDF]

open access: yes, 2019
Switching from a meat-heavy to a plant-based diet is one of the highest-impact lifestyle changes for climate mitigation and adaptation. Conventional demand-side energy policy has focused on increasing consumption of efficient machines and fuels ...
Chenyang, Lingxi
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Neighbourhood fast food exposure and consumption: the mediating role of neighbourhood social norms

open access: yesInternational Journal of Behavioral Nutrition and Physical Activity, 2020
Background The association between the residential fast food environment and diet has gained growing attention. However, why the food environment affects food consumption is under-examined.
Sofie van Rongen   +7 more
doaj   +1 more source

2014 Local Food Consumption in Vermont [PDF]

open access: yes, 2014
This paper revisits and updates a 2011 study to count local food consumption in Vermont.
Becot, Florence A., Conner, David
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Food consumption changes in South Africa since 1994

open access: yesSouth African Journal of Science, 2015
Food consumption patterns in South Africa have changed dramatically over the past decades and likely will continue to change over the coming decades. Various food-related studies conducted over the last few decades indicate that food consumption shifts ...
Lisa-Claire Ronquest-Ross   +2 more
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy