Results 61 to 70 of about 808,147 (311)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

El consumo alimenticio de la élite hidalga en Galicia durante el siglo XVIII [PDF]

Historia. Instituciones. Documentos, 2012
During the 18th century, the Galician noble elite experienced a magnificent period that was evident in a higher investment in the luxury market relative to the previous centuries. One of their most significant luxury expenses was food.
Antonio Presedo Garazo
doaj  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Neighbourhood fast food exposure and consumption: the mediating role of neighbourhood social norms

International Journal of Behavioral Nutrition and Physical Activity, 2020
Background The association between the residential fast food environment and diet has gained growing attention. However, why the food environment affects food consumption is under-examined.
Sofie van Rongen, Maartje P. Poelman, Lukar Thornton, Gavin Abbott, Meng Lu, Carlijn B. M. Kamphuis, Kirsten Verkooijen, Emely de Vet   +7 more
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Kecukupan Konsumsi Pangan Hewani di Kota Jambi dalam Hubungannya Kualitas Sumberdaya Manusia Keluarga Serta Faktor-Faktor Yang Mempengaruhinya

Jurnal Ilmiah Ilmu-Ilmu Peternakan, 2008
This  research  was  aimed  to  1)  determine the  sufficiency  of  animal  food  consumption  such  as amount  of  food  consumption,  animal  protein  and  energi  consumption  for  the  healthy  life,  2)    find  the correlation  between ...
Muhammad Farhan
doaj   +3 more sources

Positive public attitudes towards agricultural robots

Scientific Reports
Robot technologies could lead to radical changes in farming. But what does the public know and think about agricultural robots? Recent experience with other agricultural technologies—such as plant genetic engineering—shows that public perceptions can ...
Hendrik Hilmar Zeddies, Gesa Busch, Matin Qaim   +2 more
doaj   +1 more source

Food consumption changes in South Africa since 1994

South African Journal of Science, 2015
Food consumption patterns in South Africa have changed dramatically over the past decades and likely will continue to change over the coming decades. Various food-related studies conducted over the last few decades indicate that food consumption shifts ...
Lisa-Claire Ronquest-Ross, Nick Vink, Gunnar O. Sigge   +2 more
doaj   +1 more source

IMPACT Projections of Food Production, Consumption, and Hunger to 2050, With and Without Climate Change: Extended Country-level Results for 2019 GFPR Annex Table 5 [PDF]

, 2018
Policy makers, analysts, and civil society face increasing challenges to reducing hunger and improving food security in a sustainable way. Modeling alternative future scenarios and assessing their outcomes can help inform policy choices.
International Food Policy Research Institute (IFPRI)
core   +1 more source