Results 81 to 90 of about 1,650,578 (302)

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Packaging to prolong shelf life of preservative-free white bread

Heliyon, 2018
This research studied various types of packaging to prolong the shelf life of non-preservative white bread. Three types of blown film packages were used, i.e.
Settakorn Upasen, Piyachat Wattanachai
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

PERAN PROGRAM STUDI TEKNIK PANGAN (FOOD ENGINEERING) UNTUK MENUNJANG PEMBANGUNAN INDUSTRI PANGAN DI INDONESIA [The Roles of Engineering fot the Development of Agro Industries in Indonesia]

Jurnal Teknologi dan Industri Pangan, 2005
At this time more than 60 % of Indonesian population still depend on the agricultural sector. Accordingly, in future agro and food industries are expected to be the main steppingstone for the economic development in Indonesia.
Suhargo, Budi Rahardjo
doaj  

Ecosystem engineering and food web stability

Scientific Reports
Ecosystem engineering, which involves organism-triggered physical modification of the environment, is a widespread phenomenon. Despite this, the role of engineering in ecological communities remains poorly understood.
Akihiko Mougi
doaj   +1 more source

Taguchi-generalized regression neural network micro-screening for physical and sensory characteristics of bread

Heliyon, 2018
Generalized regression neural networks (GRNN) may act as crowdsourcing cognitive agents to screen small, dense and complex datasets. The concurrent screening and optimization of several complex physical and sensory traits of bread is developed using a ...
George J. Besseris
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Wet Granular Materials

, 2006
Most studies on granular physics have focused on dry granular media, with no liquids between the grains. However, in geology and many real world applications (e.g., food processing, pharmaceuticals, ceramics, civil engineering, constructions, and many ...
Albert I, Albert R, Bagnold RA, Bartelt P, Baumann G, Behringer RP, Benza VG, Bonamy D, Bowden FP, Cassel DK, Castellanos A, Cates ME, Coniglio A, Coussot P, Crassous J, D'Anna G, D'Anna G, D'Anna G, D'Anna G, de Gennes P-G, Dikau R, Duran J, Ertas D, Fierro A, Forsyth AJ, Franco Nori, Fraysse N, Fukue M, Geromichalos D, Gioia G, Géminard J-C, Hakuno M, Herminghaus S, Hertz H, Hilf JW, Ho DYF, Hornbaker DJ, Israelachvili JN, Kansai International Airport Co. Ltd., Kimura Y, Knight JB, Kristensen HG, Kudrolli A, Kézdi Á, Landau LD, Lian G, Liu AJ, Losert W, Lu N, Makse HA, Mason TG, Medved M, Melo F, Mitarai N, Mitarai N, Mitarai N, Mitarai N, Namiko Mitarai, Nase ST, Nasuno S, Nedderman RM, Newitt DM, Nicodemi M, Nicodemi M, Nicor F, Nori F, Nowak S, Oka F, Olivi-Tran N, Pak HK, Phene CJ, Phene CJ, Pierrat P, Pinkus O, Pitois O, Pöschel T, Rajchenbach J, Rajchenbach J, Reed JS, Renard S, Restagno F, Ristow GH, Ristow GH, Schell M, Schulz M, Seligman G, Shapiro LH, Tarjus G, Tegzes P, Tegzes P, Tegzes P, Van Damme H, Xu H, Xu JQ   +93 more
core   +3 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Applying Membrane Systems in Food Engineering [PDF]

, 2010
Food engineering deals with manufacturing, packaging and distributing systems for drug and food products. In this work, we discuss about the applicability of membrane systems to model environmental conditions and their e ects on the produces during ...
Dittrich, Peter, Escuela, Gabi, Hinze, Thomas, Moreno Álvarez, Mario, Schuster, Stefan   +4 more
core