A Synergistic Inhibitor Development Strategy Against Human UDP‐Galactose‐4‐Epimerase
The epimerase GalE is crucial for the biosynthesis of cancer‐relevant O‐GalNAc glycans. Here, we employ orthogonal, structurally enabled small molecule fragment screens to yield both covalent and non‐covalent inhibitors against GalE within no more than 22 elaborated compounds.
William M. Browne +22 more
wiley +1 more source
The role of ATP bioluminescence in monitoring surface hygiene in hospital settings: a comprehensive review. [PDF]
Kotsiou OS +5 more
europepmc +1 more source
Evidence of prevailing practice of home slaughter in Iran revealed by bioeconomic modeling of small ruminants slaughtered in and outside registered abattoirs. [PDF]
Ebrahimipour M +3 more
europepmc +1 more source
'Unwilling' vs. 'Unable': do domesticated dogs choose partners based on their intentional actions? [PDF]
Choi Y, Santos LR.
europepmc +1 more source
Functional morphology of the pharyngeal teeth of the ocean sunfish, Mola mola
Abstract Many fish use a set of pharyngeal jaws in their throat to aid in prey capture and processing, particularly of large or complex prey. In this study—combining dissection, CT scanning, histology, and performance testing—we demonstrate a novel use of pharyngeal teeth in the ocean sunfish (Mola mola), a species for which pharyngeal jaw anatomy had ...
Benjamin Flaum +3 more
wiley +1 more source
Risk assessment for Brucella suis biovar 2 in Danish pigs. [PDF]
Alban L, Dresling A, Poulsen MK.
europepmc +1 more source
Abstract New data on the equine aortic valve obtained using advanced techniques is especially important given the greater availability of animal models for translational research. Here we characterized the morphological and morphometric aspects of the equine aortic valve from 60 healthy hearts collected at equine abattoirs.
Vitor Pires Pereira +3 more
wiley +1 more source
Performance assessment of ISO 23036-1:2021 for parasite detection in the seafood industry. [PDF]
Rodríguez H +4 more
europepmc +1 more source
Broadening the semiaquatic scene: Quantification of long bone microanatomy across pinnipeds
Abstract Investigations of bone microanatomy are commonly used to explore lifestyle strategies in vertebrates. While distinct microanatomical limb bone features have been established for exclusively aquatic and terrestrial lifestyles, identifying clear patterns for the semiaquatic lifestyle remains more challenging.
Apolline Alfsen +10 more
wiley +1 more source
Regulatory responses to foodborne illness outbreaks in the United States and their implications for food safety. [PDF]
Prabhukhot G.
europepmc +1 more source

