Results 31 to 40 of about 3,140,769 (306)

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

Labeling of genetically modified food and consumers' rights [PDF]

Zbornik Radova: Pravni Fakultet u Novom Sadu, 2014
The legal regulation of genetically modified food directly affects consumers, since they are the ones who encounter genetically modified food on the shelves every day.
Vujisić Dragan, Mihajlović Borko
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Study of awareness of food labeling among consumers in North-West Russia [PDF]

E3S Web of Conferences, 2020
A survey among the consumers of North-Western region of Russia (St. Petersburg and Leningradskaya oblast) was carried out, to determine awareness and understanding of food labeling, as well as usefulness of various elements of food labeling.
Shamtsyan Mark, Kolesnikov Boris, Pushkarev Mikhail, Gaceu Liviu, Oprea Oana Bianca, Iatco Iulia, Mnerie Dumitru, Mnerie Gabriela, Tita Ovidiu, Tita Mihaela, Georgescu Checilia, Mironescu Monica, Stefanov Stefan, Damianova Stanka   +13 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Food Allergen Testing Standards and Labeling Status

Shipin gongye ke-ji, 2022
With the continuous improvement of people's living standards and health awareness, more and more attention has been paid to food safety. It follows that the research and management of the types and labels of food allergens also need to be more and more ...
Ruoting YANG, Zhiyong DAI, Lina PAN, Xiaoyu PENG, Xin LI, Hongbing CHEN   +5 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

A Decision-Making Model for Deterring Food Vendors from Selling Harmless Low-Quality Foods as High-Quality Foods to Consumers

Journal of Food Quality, 2017
For certain types of foods, food vendors often label low-quality foods that are harmless to human health as foods of excellent quality and sell these falsely labeled products to consumers.
Po-Yu Chen
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Food labelling

European Journal of Public Health, 2022
Abstract The Commission has undertaken to regulate the information provided to consumers on food. In particular, it intends to propose mandatory front-of-pack nutrition labelling (FoPNL) for food by the end of 2022. Even though nutrition labelling has been regulated by the EU since 1990, the tactics of industry, with the support of a ...
openaire   +1 more source