Results 41 to 50 of about 392,753 (302)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Dietary Biomarkers of Vegetable and Fruit Intake in Asians: An Epidemiological Systematic Review

Dietetics
Accurate estimation of food intake is necessary to clarify the relationship between dietary intake and particular health conditions; however, self-reported assessments often result in estimation errors.
Yuko Tousen, Reina Ikaga, Ai Yasudomi, Naho Sasaki, Toshiro Kobori, Masuko Kobori, Hidemi Takimoto   +6 more
doaj   +1 more source

A Decision-Making Model for Deterring Food Vendors from Selling Harmless Low-Quality Foods as High-Quality Foods to Consumers

Journal of Food Quality, 2017
For certain types of foods, food vendors often label low-quality foods that are harmless to human health as foods of excellent quality and sell these falsely labeled products to consumers.
Po-Yu Chen
doaj   +1 more source

Potential effect of different nutritional labels on food choices among mothers: a study protocol

BMC Public Health, 2020
Background The prevalence of non-communicable diseases (NCDs) is increasing in the world. Healthy food choice and adequate physical activity are key factors in preventing NCDs.
Shirin Seyedhamzeh, Saharnaz Nedjat, Hedayat Hosseini, Elham Shakibazedeh, Anthony J. Viera, Ahmadreza Dorosty Motlagh   +5 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Decoding Food Labels: Handouts for People with Food Allergies

EDIS, 2017
Full-page handouts for people with food allergies, to eggs, milk, peanuts, soy, and wheat. Lists for each allergen label terms to avoid and types of foods that contain it. Updated with photo illustrations.
Amy Simonne, Elizabeth Gollub
doaj   +5 more sources

Young Consumer’s Awareness on Food Packet Labeling in Rural Tamil Nadu – A Convergent Mixed Methods Study

Journal of the Scientific Society
Background: Food labeling is one medium by which consumers can acquire knowledge about the food they consider buying. This type of information is becoming increasingly important in a food market where direct contact with personnel over the counter is ...
Saranya Selvamurthy, M. Rajalakshmi, Reenaa Mohan, K. Premanandh   +3 more
doaj   +1 more source

Genetically Modified Labeling Policies: Moving Forward or Backward?

Frontiers in Bioengineering and Biotechnology, 2018
One of the priorities to address food security is to increase the access of farmers to biotechnology, through the application of scientific advances, such as genetically modified organisms and food (GMF).
Bárbara Juliana Pinheiro Borges, Olivia Márcia Nagy Arantes, Antonio Alberto Ribeiro Fernandes, James R. Broach, Patricia Machado Bueno Fernandes, Patricia Machado Bueno Fernandes   +5 more
doaj   +1 more source