Results 181 to 190 of about 3,815,501 (279)
Mapping Sustainability Innovation Performance and Its Management: An Integrative Framework
Business Strategy and the Environment, EarlyView.ABSTRACT Sustainability innovation performance (SIP) has become central to how organizations innovate, yet the field remains fragmented: Terms are used inconsistently, measures are nonstandardized, and reviews rarely integrate its layers. Drawing on a systematic review of 53 peer‐reviewed articles, we develop the Sustainability Innovation Management ...
Claudia Löckner +2 more
wiley +1 more source
Biotechnology Progress, EarlyView.Abstract Development of therapeutic bispecific antibodies (BsAbs) poses significant manufacturability challenges associated with correct chain pairing and an increased diversity of impurities. Here we address this with a product quality assessment during cell line development (CLD), forgoing the need for genetic characterization during cell line ...
Molly Robinson +7 more
wiley +1 more source
Regenerative perfusion bioreactor for biologics production with lower COGs
Biotechnology Progress, EarlyView.Abstract Perfusion bioreactor systems enable intensified bioprocessing with high cell densities and volumetric productivities in monoclonal antibody (mAb) manufacturing. However, their widespread adoption remains constrained by the high consumption of chemically defined cell culture media.
Eric Wynne +5 more
wiley +1 more source
Bone marrow‐like viscosity affects imatinib resistance in chronic myeloid leukemia
Biotechnology Progress, EarlyView.Physical cues such as microenvironmental viscosity have been recognized as important regulators in controlling cell functions. However, even though the bone marrow (BM) is a viscous tissue in which cells respond mechanically to both the matrix stiffness and the viscosity of surrounding fluid, the impact of microenvironmental viscosity on imatinib (IM ...
Tianjiao Zeng +6 more
wiley +1 more source
Biotechnology Progress, EarlyView.Abstract Recombinant adeno‐associated virus production for gene therapy applications commonly relies on the Spodoptera frugiperda 9 (Sf9) baculovirus infection platform. The process encompasses cell expansion from flasks through intermediate‐scale bioreactors to large‐scale production.
Min Tae Park, Seyed Pouria Motevalian
wiley +1 more source
Biotechnology Progress, EarlyView.SIM‐CaliRam combines simulation‐informed references and biomass‐augmented features for in‐line Raman calibration under sparse labels and biomass‐induced spectral confounding. Run‐wise calibration and validation enable prediction of biomass, glucose, ammonium, and phosphate on an unseen S. cerevisiae fed‐batch fermentation.
Terrance Wilms, Steffi Knorn
wiley +1 more source
because microbiology is an exeptionally broad discipline encompassing speciaties as diverse as biochemistry, cell biology, genetics, taxonomy, pathogenetic, food and indrustrial microbiology and ecology, our goal has been to provide a balanced ...
PRESCOTT, Lansing M.
core
Biotechnology Progress, EarlyView.Flocculation using cationic polymers leads to the creation of large floc complexes. Negative charged species like cells, cell debris, and negatively charged host cell impurities like host cell DNA and host cell proteins are trapped within the complex while the positively charged monoclonal antibody stays in solution.
Anna‐Carina Frank +9 more
wiley +1 more source
Optimizing Instant Rice Quality of Milled and Brown Rice Through Cultivar‐Selection
Cereal Chemistry, EarlyView.ABSTRACT Background and Objectives Instant rice products are increasingly favored for convenience; however, achieving consistent quality, particularly rehydration performance and texture, remains a challenge. Rice cultivars differ in physicochemical properties that influence processing behavior and final product quality, yet systematic screening ...
Faith Ouma +2 more
wiley +1 more source