Results 81 to 90 of about 907,081 (308)

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Cooking Skills in Health Professionals: A Systematic Review

Dietetics
Cooking skills (CSs) encompass both physical and behavioral abilities, and their transmission has evolved due to social changes and the rise of fast food as a convenient but unhealthy option.
Letícia M. Conceição, Sara S. P. Rodrigues   +1 more
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Exploring the Returns to Scale in Food Preparation (Baking Penny Buns at Home) [PDF]

We show that as household size increases, households substitute away from prepared foods and towards ingredients. They also devote more time to food preparation.
Yuqian Lu, Thomas F. Crossley
core   +2 more sources

The Preparation of Liebig's Food [PDF]

The Boston Medical and Surgical Journal, 1884
n ...
openaire   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Food Preparation Studies [PDF]

, 1974
Abstract : The 42-day menu cycle was analyzed in terms of equipment required for the Central Food Preparation and Satellite Food Service Facilities. Commercial equipment that can perform the various unit processes and unit operations was listed. With few exceptions, practically all the equipment needs can be satisfied by existing designs.
Charles J. Rogers, Samson T. Hsia, Thomas R. Parks   +2 more
openaire   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Exploring the Returns-to-Scale in Food Preparation [PDF]

We show that as household size increases, households substitute away from prepared foods and towards ingredients. They also devote more time to food preparation.
Yuqian Lu, Thomas F. Crossley
core  

A Matter of Preparation: Investigating the Differential Effects of Disassembling and Cooking on Meat-Related Perceptions and Conflict

Psychology of Human-Animal Intergroup Relations
Food preparation plays a key role in shaping how people perceive meat: It helps people to dissociate meat from its animal origin and allows them to eat meat without experiencing conflict.
Benjamin Buttlar, Lena Hahn, Monique Chambon   +2 more
doaj   +1 more source