Results 61 to 70 of about 7,760,995 (367)
Background The Office of Orphan Products Development (OOPD) of the United States (U.S.) Food and Drug Administration (FDA) has awarded over 700 grants to conduct clinical trials of medicals products for rare diseases since 1983, leading to over 70 ...
Kathleen L. Miller+4 more
doaj +1 more source
LHCPs are transported to the thylakoid membrane via the (cp)SRP pathway. This process involves a transit complex of (cp)SRP43, (cp)SRP54 and LHCP, which interacts with (cp)FtsY and Alb3 at the membrane. GTP hydrolysis by (cp)SRP54 and (cp)FtsY triggers complex dissociation.
Victor Zegarra+7 more
wiley +1 more source
Prediction of Food Production Using Machine Learning Algorithms of Multilayer Perceptron and ANFIS [PDF]
Advancing models for accurate estimation of food production is essential for policymaking and managing national plans of action for food security. This research proposes two machine learning models for the prediction of food production. The adaptive network-based fuzzy inference system (ANFIS) and multilayer perceptron (MLP) methods are used to advance
arxiv
Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga+6 more
wiley +1 more source
Norovirus is the leading cause of acute gastroenteritis worldwide. For over two decades, a single genotype (GII.4) has been responsible for most norovirus-associated cases. However, during the winter of 2014 to 2015, the GII.4 strains were displaced by a
Kentaro Tohma+3 more
doaj +1 more source
Effective tiller number (ETN) is an important factor affecting plant architecture and wheat yield. The reduction of genetic diversity in common wheat breeding forces us to explore new genetic resources for ETN from wheat related species to increase wheat
Li Chen+4 more
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Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze+3 more
wiley +1 more source
Abstract The present study was conducted as part of a comprehensive work to establish National Diagnostic Reference Levels (NDRLs) in Sri Lanka for the first time. DRLs can be used as an effective optimization tool for identifying unusually high or low patient doses during X‐ray examinations.
Sachith Welarathna+3 more
wiley +1 more source
Food crisis, food production and poverty [PDF]
There is a sufficient global potential to produce the food required to feed the world population on the global level. Despite this, the number of hungry people worldwide was 925 million in 2010. Developing countries account for 98% of the world undernourished people and have a prevalence of undernourishment of 16%. Food security increasingly depends on
Š. Grófová, Karel Srnec
openaire +3 more sources
In-depth characterisation of the lamb meat proteome from longissimus lumborum
Lamb is one of the major red meats consumed globally, both as a key component in the diet of some countries, and as a niche meat product in others. Despite this relatively wide consumption, an in-depth description of the global protein composition of ...
Tzer-Yang Yu+3 more
doaj +1 more source