Results 61 to 70 of about 8,000,776 (354)

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

A comprehensive proteomics profiling identifies NRP1 as a novel identity marker of human bone marrow mesenchymal stromal cell-derived small extracellular vesicles

open access: yesStem Cell Research & Therapy, 2019
Background Clinical applications have shown extracellular vesicles (EVs) to be a major paracrine effector in therapeutic responses produced by human mesenchymal stromal/stem cells (hMSCs).
Afnan Munshi   +14 more
doaj   +1 more source

Genetic identification of a major, novel and stably expressed QTL for effective tiller number from tetraploid wheat

open access: yesBiotechnology & Biotechnological Equipment, 2021
Effective tiller number (ETN) is an important factor affecting plant architecture and wheat yield. The reduction of genetic diversity in common wheat breeding forces us to explore new genetic resources for ETN from wheat related species to increase wheat
Li Chen   +4 more
doaj   +1 more source

DEVELOPMENT OF SPECIALIZED FOOD PRODUCTS FOR NUTRITION OF SPORTSMEN

open access: yesJournal of Critical Reviews, 2020
The article is based on the relevance of the development and production of specialized food products for nutrition of athletes, aimed at solving the problem of maintaining the appropriate physical condition of the population engaged in sports, fitness in
N. Gavrilova   +7 more
semanticscholar   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Data for in-depth characterisation of the lamb meat proteome from longissimus lumborum

open access: yesData in Brief, 2015
This Data article provides Supplementary data related to the research article titled “In-depth characterisation of the lamb meat proteome from longissimus lumborum” by Yu et al. [1].
Tzer-Yang Yu   +3 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Amine-Functionalized- Mesoporous Silica Nanoparticles by Various Pore Sizes Containing Gallic Acid: Characterization and Cytotoxicity Effect [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering
Mesoporous Silica Nanoparticles (MSNs) with varying pore sizes of 2.4, 2.44, and 3.44 nm were synthesized and functionalized using 3-aminopropyltriethoxysilane (AP-MSNs), followed by the loading of Gallic Acid (GA) to produce AP-MSNs-GA.
Ladan Rashidi   +4 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

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