Results 141 to 150 of about 6,125,392 (393)
Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza+3 more
wiley +1 more source
Exploring hybridity in food supply chains [PDF]
In recent years, a number of dynamic aspects of food supply chains have attracted great interest among social scientists investigating rural restructuring and change. These include: the expansion of organic agriculture; the development of new value added
Kirwan, James, Slee, William
core +1 more source
Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza+5 more
wiley +1 more source
The food and water crisis [PDF]
Food production, Food supply, Urban agriculture, Water ...
International Water Management Institute (IWMI).
core
The four food systems in developing countries and the challenges of modern supply chain inclusion for organic small-holders [PDF]
To promote developmental objectives, such as growth, food security and improvement of the livelihoods of the rural poor, a greater understanding of the four food systems prevalent in the South is of great importance.
Kledal, P.R.
core
The notion of toxin-free food may be more of a fantasy than a factual reality. To help identify and prioritize health risks associated with long-term consumption of harmful substances and especially of natural toxins through food, a dedicated study was ...
Rudolf KRSKA+3 more
doaj +1 more source
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha+10 more
wiley +1 more source
A framework for the design and analysis of incentive systems for food safety control in supply chains [PDF]
Since 2005 the EU food industry has primary legal responsibility for food safety control. This requires new responsibilities and relationships between government and industry, and between companies.
Backus, Ge B.C.+3 more
core +1 more source