Results 91 to 100 of about 3,125,589 (355)

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

open access: yesFEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani   +7 more
wiley   +1 more source

Agri-Food Traceability Management using a RFID System with Privacy Protection [PDF]

open access: yes, 2007
In this paper an agri-food traceability system based on public key cryptography and Radio Frequency Identification (RFID) technology is proposed. In order to guarantee safety in food, an efficient tracking and tracing system is required.
Bernardi, Paolo   +5 more
core   +2 more sources

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

open access: yesFEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito   +3 more
wiley   +1 more source

Carbon Dots-Types, Obtaining and Application in Biotechnology and Food Technology. [PDF]

open access: yesInt J Mol Sci, 2023
Szczepankowska J   +3 more
europepmc   +1 more source

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

open access: yesFEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

Food Technology forecasting: A based bibliometric update in functional chocolates. [PDF]

open access: yesHeliyon, 2023
Balcázar-Zumaeta CR   +4 more
europepmc   +1 more source

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