Results 41 to 50 of about 161,700 (312)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Effects of Different Cooking Methods on the Quality of Golden Pomfret Fillets

open access: yesShipin gongye ke-ji
To investigate the differences in the quality characteristics of golden pomfret (Trachinotus ovatus) fillets under various cooking methods, a comparative study was conducted to analyze the impacts of three commonly used cooking methods, namely steaming ...
Keyi YUAN   +9 more
doaj   +1 more source

Contribution of NOVA food groups to energy and nutrient supply in Mexican households

open access: yesSalud Pública de México, 2019
Objective. To analyze the contribution of natural, processed and ultra-processed foods to energy and nutrient supply in Mexican households. Materials and methods.
Mariana Romo-Aviles   +1 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

A Framework for Food Supply Chain Digitalisation: Lessons from Thailand

open access: yes, 2020
The promise of digitalisation is enormous and nowhere is it more critical than in its potential to transform food supply chain. Consumers have become more educated and are demanding real-time updated information on foods they consumed through digital ...
Tan, Kim Hua   +1 more
core   +1 more source

The impact of climate and societal change on food and nutrition security: A case study of Malawi

open access: yesFood and Energy Security, 2021
Society is currently facing an unprecedented challenge in terms of achieving food and nutrition security for a rapidly expanding global population while also minimising and reversing damage to the natural environment.
Charlotte Hall   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Native American foods: History, culture, and influence on modern diets

open access: yesJournal of Ethnic Foods, 2016
Approximately 12,000–15,000 years ago people from northeast Asia crossed the Bering Land Bridge to enter and inhabit North America beginning in Alaska but rapidly spreading throughout North and South American and the Caribbean islands.
Sunmin Park   +2 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

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