Results 11 to 20 of about 36,586 (262)

Dynamic Changes in Plasma Metabolic Profiles Reveal a Potential Metabolite Panel for Interpretation of Fatal Intoxication by Chlorpromazine or Olanzapine in Mice

open access: yesMetabolites, 2022
Diagnosing the cause of fatal intoxication by antipsychotic agents is an important task in forensic practice. In the 2020 Annual Report of the American Association of Poison Control Centers, among 40 deaths caused by antipsychotics, 21 cases were ...
Rui Bai   +7 more
doaj   +1 more source

An interpretation of the genetic polymorphism and population genetic background of Ankang Han population via a novel InDel panel

open access: yesForensic Sciences Research, 2021
In this research, genotyping data of 43 InDel loci in 311 Han individuals in Ankang city, Shaanxi province, China were detected using a self-developed five-dye multiplex amplification panel.
Wei Cui   +8 more
doaj   +1 more source

Inference in Forensic Identification

open access: yesJournal of the Royal Statistical Society. Series A (Statistics in Society), 1995
The problem of quantifying the weight of evidence in forensic identification is addressed. The essence of the problem is abstracted in a simple paradigm, the analysis of which yields valuable insights and highlights important distinctions. A special case of this analysis gives a resolution of the so-called island problem.
Balding, D, Donnelly, P
openaire   +1 more source

Identification of IoT Devices for Forensic Investigation [PDF]

open access: yes2020 IEEE 10th International Conference on Intelligent Systems (IS), 2020
As the Internet of Things (IoT) environment rapidly grows, so do the distribution and utilisation of IoT devices as well as Cyber-Enabled and Dependent Crime activities. This leads to challenges investigators face when forensically investigating the IoT to present evidence in the court of law.
Nancy Scheidt, Mo Adda
openaire   +1 more source

Inhibitory Effect of CCK-8 on Methamphetamine-Induced Apoptosis

open access: yesFayixue Zazhi, 2021
ObjectiveTo investigate the inhibitory effect of cholecystokinin octapeptide (CCK-8) binding to cholecystokinin 2 receptor (CCK2R) on methamphetamine (METH)-induced neuronal apoptosis, and to explore the signal transduction mechanism of β-arrestin 2 in ...
ZHANG Wu-hua   +8 more
doaj   +1 more source

The amino acid metabolomics signature of differentiating myocardial infarction from strangulation death in mice models

open access: yesScientific Reports, 2023
This study differentiates myocardial infarction (MI) and strangulation death (STR) from the perspective of amino acid metabolism. In this study, MI mice model via subcutaneous injection of isoproterenol and STR mice model by neck strangulation were ...
Song-Jun Wang   +7 more
doaj   +1 more source

Gut microbiota from sigma-1 receptor knockout mice induces depression-like behaviors and modulates the cAMP/CREB/BDNF signaling pathway

open access: yesFrontiers in Microbiology, 2023
IntroductionDepression is a common mental disorder that affects approximately 350 million people worldwide. Much remains unknown about the molecular mechanisms underlying this complex disorder. Sigma-1 receptor (Sig-1R) is expressed at high levels in the
Jia-Hao Li   +8 more
doaj   +1 more source

Endoplasmic Reticulum Stress Is Involved in Glucocorticoid-Induced Apoptosis in PC12 Cells

open access: yesAnalytical Cellular Pathology, 2021
Objective. The present study selected PC12 cells to construct a neuronal injury model induced by glucocorticoids (GC) in vitro, aiming to explore whether the endoplasmic reticulum stress (ERS) PKR-like endoplasmic reticulum kinase (PERK)-activating ...
Shanyong Yi   +7 more
doaj   +1 more source

New Advances, Challenges and Opportunities in Forensic Applications of Microbiomics

open access: yesFayixue Zazhi, 2022
The succession of microbiota is closely associated with several essential factors, including race, sex, health condition, lifestyle, postmortem interval, etc., and it has great potential application value in forensic medicine.
LEI Fan-zhang   +4 more
doaj   +1 more source

A Metabolomics-Based Study on the Discriminative Classification Models and Toxicological Mechanism of Estazolam Fatal Intoxication

open access: yesMetabolites, 2023
Fatal intoxication with sedative-hypnotic drugs is increasing yearly. However, the plasma drug concentration data for fatal intoxication involving these substances are not systematic and even overlap with the intoxication group.
Xiaohui Dai   +9 more
doaj   +1 more source

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