Results 121 to 130 of about 15,036 (214)
, 2009 Review on FOXO1 (Forkhead box O1), with data on DNA, on the protein encoded, and where the gene is ...
Barr, FG, O'Connor, R
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Different anti-adipogenic effects of bio-compounds on primary visceral pre-adipocytes and adipocytes. [PDF]
, 2016 Several natural compounds exhibit strong capacity for decreasing triglyceride accumulation, enhancing lipolysis and inducing apoptosis. The present study reports the anti-adipogenic effects of Silybum marianum (SL), Citrus aurantium (CA), Taraxacum ...
Colitti, Monica, Stefanon, Bruno
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Communications BiologyDecidualization of human endometrial stromal cells (HESCs) is one of the critical steps in the establishment of human pregnancy. Nevertheless, little is known about the molecular mechanisms underlying human decidualization.
Yuying Guo +8 more
doaj +1 more source
Computational modelling of the regulation of Insulin signalling by oxidative stress [PDF]
, 2013 BACKGROUND: Existing models of insulin signalling focus on short term dynamics, rather than the longer term dynamics necessary to understand many physiologically relevant behaviours.
Daryl P Shanley, Graham R Smith
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Stem Cells International, 2019 Periodontitis is a chronic disease that includes the pathologic loss of periodontal tissue and alveolar bone. The inflammatory environment in periodontitis impairs the osteogenic differentiation potential and depresses the regeneration capacity of human ...
Xiaojun Huang +5 more
doaj +1 more source
Regulation of IL-6-signaling and inflammatory response – Role of insulin, FOXO1 and PKCδ [PDF]
, 2010 The aim of this thesis was to investigate if and how insulin antagonizes interleukin-6 (IL-6)-signaling and action using both 3T3-L1 mouse adipocytes (Paper I) and HepG2 human hepatocytes (Paper III).
Wallerstedt, Emelie
core
FoxO3 transcription factor and Sirt6 deacetylase regulate LDL-cholesterol homeostasis via control of the proprotein convertase subtilisin/kexin type 9 (Pcsk9) gene expression [PDF]
, 2013 Elevated LDL-cholesterol is a risk factor for the development of cardiovascular disease. Thus, proper control of LDL-cholesterol homeostasis is critical for organismal health.
Deng, Chu-Xia +4 more
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Antioxidative fullerol promotes osteogenesis of human adipose-derived stem cells
International Journal of Nanomedicine, 2014 Xinlin Yang, Ching-Ju Li, Yueping Wan, Pinar Smith, Guowei Shang, Quanjun Cui Department of Orthopaedic Surgery, University of Virginia School of Medicine, Charlottesville, VA, USA Abstract: Antioxidants were implicated as potential reagents to enhance
Yang XL +5 more
doaj
Cellular and Molecular Life SciencesEndometriosis is a hormone dependent disease that often accompanies infertility. At present, the incidence rate of endometriosis is on the rise, but its pathogenesis and the mechanism leading to fertility reduction are still unclear. Here, we report that
Fangyuan Sun +10 more
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Caloric restriction blocks neuropathology and motor deficits in Machado–Joseph disease mouse models through SIRT1 pathway [PDF]
, 2015 Machado–Joseph disease (MJD) is a neurodegenerative disorder characterized by an abnormal expansion of the CAG triplet in the ATXN3 gene, translating into a polyglutamine tract within the ataxin-3 protein.
Carmona, Vitor +5 more
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