Regulation of insulin-like growth factor–dependent myoblast differentiation by Foxo forkhead transcription factors [PDF]
Marta Letizia Hribal+4 more
openalex +1 more source
Addressing complexity in the study of life sciences through Systems Biology and Systems Medicine has been transformative, making Systems Pharmacology the next logical step. In this review, we focus on physical stimuli, whose potential in pharmacology has been neglected, despite demonstrated therapeutic properties.
Veronica Paparozzi+10 more
wiley +1 more source
Understanding the perspectives of forkhead transcription factors in delayed wound healing. [PDF]
Rajendran NK+3 more
europepmc +1 more source
The forkhead protein Fkh2 is a component of the yeast cell cycle transcription factor SFF
Aline Pic‐Taylor+9 more
openalex +1 more source
PBK Expression Promotes the Aggressive Phenotypes of Mesothelioma
PBK plays a crucial role in cell survival in mesothelioma and is associated with worse outcome. PBK is a promising therapeutic target that may serve as a prognostic biomarker, enabling personalized treatment of mesothelioma. ABSTRACT Mesothelioma is one of the most aggressive neoplasms worldwide that has a particularly poor prognosis.
Kazumi Hori+12 more
wiley +1 more source
Mutational analysis of forkhead transcriptional factor 2 (FOXL2) in Korean patients with blepharophimosis–ptosis–epicanthus inversus syndrome [PDF]
SC Cha+8 more
openalex +1 more source
Endothelial‐mesenchymal transition (EndoMT) contributes to neuroendocrine differentiation (NED) in prostate cancer. Using in vitro co‐culture models, we show that EndoMTed endothelial cells promote NED in prostate cancer cells via GM‐CSF signaling. These findings reveal a previously unrecognized paracrine mechanism by which the tumor microenvironment ...
Takumi Kageyama+11 more
wiley +1 more source
Bidirectional regulation of osteogenic differentiation by the FOXO subfamily of Forkhead transcription factors in mammalian MSCs. [PDF]
Chen D+5 more
europepmc +1 more source
Regulation of PGC-1 Promoter Activity by Protein Kinase B and the Forkhead Transcription Factor FKHR [PDF]
Hiroaki Daitoku+4 more
openalex +1 more source
During hypoxia, the transcriptional effect of super‐enhancer in promoting CBP/p300‐interacting transactivator with Glu/Asp‐rich C‐terminal domain, 2 reduced, eventually leading to the thickening of the smooth muscle layer of the pulmonary artery.
Songyue Li+11 more
wiley +1 more source