Loss of expression and nuclear/cytoplasmic localization of the FOXP1 forkhead transcription factor are common events in early endometrial cancer: relationship with estrogen receptors and HIF-1α expression [PDF]
, 2005 Alexandra Giatromanolaki +5 more
openalex +1 more source
Reactive Oxygen Species: From Tumorigenesis to Therapeutic Strategies in Cancer
Cancer Medicine, Volume 14, Issue 10, May 2025.ABSTRACT Background Reactive oxygen species (ROS), a class of highly reactive molecules, are closely linked to the pathogenesis of various cancers. While ROS primarily originate from normal cellular processes, external stimuli can also contribute to their production. Cancer cells typically exhibit elevated ROS levels due to disrupted redox homeostasis,
Iqra Attique +6 more
wiley +1 more source
An Update on the Nutritional and Therapeutic Potential of Dioscorea oppositifolia
Food Science &Nutrition, Volume 13, Issue 5, May 2025.Dioscorea oppositifolia L. (Cinnamon vine) contains bioactive compounds, such as diosgenin, demonstrating anticancer properties. Diosgenin inhibits JAK/STAT3 signaling, suppressing cell proliferation, invasion and metastasis. Additionally, it triggers mitochondrial apoptosis by activating Bax, promoting cytochrome C release and stimulating caspase‐9 ...
Ruchika Kumari +10 more
wiley +1 more source
Coordination of NF-κB and NFAT Antagonism by the Forkhead Transcription Factor Foxd1 [PDF]
, 2006 Ling Lin, Stanford L. Peng
openalex +1 more source
Role of Extracellular Vesicles in the Pathogenesis of Brain Metastasis
Journal of Extracellular Biology, Volume 4, Issue 5, May 2025.ABSTRACT Extracellular vesicles (EVs) are small particles released by various cells, including cancer cells. They play a significant role in the development of different cancers, including brain metastasis. These EVs transport biomolecular materials such as RNA, DNA, and proteins from tumour cells to other cells, facilitating the spread of primary ...
Muhammad Izhar, Maciej S. Lesniak
wiley +1 more source
Expression of the forkhead transcription factor FoxN4 in progenitor cells in the developing Xenopus laevis retina and brain [PDF]
, 2006 Lisa E. Kelly +2 more
openalex +1 more source
The Kaohsiung Journal of Medical Sciences, Volume 41, Issue 5, May 2025.ABSTRACT Proteasome 26S subunit non‐ATPase 14 (PSMD14) plays a pro‐carcinogenic role in various cancers. However, its specific effects and mechanisms in pancreatic cancer (PC) remain unclear. We aimed to assess the function and mechanism of PSMD14 in PC.
Yun‐He Hao +3 more
wiley +1 more source
Alopecia Areata: Pathogenesis, Diagnosis, and Therapies
MedComm, Volume 6, Issue 5, May 2025.This review probed into the immune factors in the pathogenesis of AA, focusing on the small molecule drugs and biologics for the treatment of AA, and anticipated the research direction in terms of the pathogenesis and targeted therapy of AA. It aims to emphasize the necessity for further exploration of its immunological pathogenesis and therapeutic ...
Tianyou Ma +7 more
wiley +1 more source
Forkhead transcription factors regulate mosquito reproduction [PDF]
, 2007 Immo A. Hansen +7 more
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Organoid‐Guided Precision Medicine: From Bench to Bedside
MedComm, Volume 6, Issue 5, May 2025.This review focuses on the structural and characterization aspects of organoids derived from original cells and scaffold materials. It also examines the construction methodologies, the incorporation of cytokines, and the practical applications in precision medicine.
Boqiang Tao +12 more
wiley +1 more source