Results 151 to 160 of about 56,919 (302)

Regulation of insulin-like growth factor–dependent myoblast differentiation by Foxo forkhead transcription factors [PDF]

open access: bronze, 2003
Marta Letizia Hribal   +4 more
openalex   +1 more source

Anti‐inflammatory effects of physical stimuli: The central role of networks in shaping the future of pharmacological research

open access: yesBritish Journal of Pharmacology, EarlyView.
Addressing complexity in the study of life sciences through Systems Biology and Systems Medicine has been transformative, making Systems Pharmacology the next logical step. In this review, we focus on physical stimuli, whose potential in pharmacology has been neglected, despite demonstrated therapeutic properties.
Veronica Paparozzi   +10 more
wiley   +1 more source

Understanding the perspectives of forkhead transcription factors in delayed wound healing. [PDF]

open access: yesJ Cell Commun Signal, 2019
Rajendran NK   +3 more
europepmc   +1 more source

The forkhead protein Fkh2 is a component of the yeast cell cycle transcription factor SFF

open access: green, 2000
Aline Pic‐Taylor   +9 more
openalex   +1 more source

PBK Expression Promotes the Aggressive Phenotypes of Mesothelioma

open access: yesCancer Science, EarlyView.
PBK plays a crucial role in cell survival in mesothelioma and is associated with worse outcome. PBK is a promising therapeutic target that may serve as a prognostic biomarker, enabling personalized treatment of mesothelioma. ABSTRACT Mesothelioma is one of the most aggressive neoplasms worldwide that has a particularly poor prognosis.
Kazumi Hori   +12 more
wiley   +1 more source

Endothelial‐Mesenchymal Transition in Tumor Microenvironment Promotes Neuroendocrine Differentiation of Prostate Cancer

open access: yesCancer Science, EarlyView.
Endothelial‐mesenchymal transition (EndoMT) contributes to neuroendocrine differentiation (NED) in prostate cancer. Using in vitro co‐culture models, we show that EndoMTed endothelial cells promote NED in prostate cancer cells via GM‐CSF signaling. These findings reveal a previously unrecognized paracrine mechanism by which the tumor microenvironment ...
Takumi Kageyama   +11 more
wiley   +1 more source

Regulation of PGC-1 Promoter Activity by Protein Kinase B and the Forkhead Transcription Factor FKHR [PDF]

open access: bronze, 2003
Hiroaki Daitoku   +4 more
openalex   +1 more source

Super‐Enhancer Target Gene CBP/p300‐Interacting Transactivator With Glu/Asp‐Rich C‐Terminal Domain, 2 Cooperates With Transcription Factor Forkhead Box J3 to Inhibit Pulmonary Vascular Remodeling

open access: yesCell Proliferation, EarlyView.
During hypoxia, the transcriptional effect of super‐enhancer in promoting CBP/p300‐interacting transactivator with Glu/Asp‐rich C‐terminal domain, 2 reduced, eventually leading to the thickening of the smooth muscle layer of the pulmonary artery.
Songyue Li   +11 more
wiley   +1 more source

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