Results 171 to 180 of about 94,249 (285)

Antibiotic‐mediated immune modulation in periodontitis

open access: yesPeriodontology 2000, EarlyView.
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez   +6 more
wiley   +1 more source

From senescence and inflammaging to systemic comorbidities: Drivers of aging‐associated periodontitis

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Aging is accompanied by a chronic low‐grade inflammatory process, known as inflammaging, as well as immunosenescence, an age‐related decline and dysregulation of immune function, and cellular senescence, a process in which cells enter a state of irreversible growth arrest while actively releasing pro‐inflammatory factors.
James Cheng   +4 more
wiley   +1 more source

Structure of the forkhead domain of FOXP2 bound to DNA [PDF]

open access: yes, 2006
Bates, D.   +7 more
core   +2 more sources

Dbf4 recruitment by forkhead transcription factors defines an upstream rate-limiting step in determining origin firing timing. [PDF]

open access: yesGenes Dev, 2017
Fang D   +10 more
europepmc   +1 more source

Evaluation of the Cutaneous Immunological Milieu Before and After Treatment With Meglumine Antimoniate in Dogs Naturally Affected by Leishmaniosis due to Leishmania infantum

open access: yesVeterinary Dermatology, EarlyView.
Background: Canine leishmaniosis (CanL) is a zoonotic disease of variable severity. The typical immune response is driven by an exaggerated humoral immune response. Protective immunity is mediated by pro‐inflammatory cytokines that enhance macrophage leishmanicidal activity. Objective: To evaluate the cutaneous and the systemic immune responses as well
M. Platenik   +5 more
wiley   +1 more source

Senolytics and exercise: Dual modalities for rejuvenating muscle

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The role of senolytics on the heart and skeletal muscle. Senescent cell burden increases with ageing, disuse and disease. The senolytics dasatinib+quercetin (D+Q), navitoclax and fisetin, as well as exercise, eliminate senescent cells, reducing senescent cell burden and their senescence‐associated secretory phenotype (SASP ...
Zeynep Elif Yesilyurt‐Dirican   +4 more
wiley   +1 more source

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