Results 191 to 200 of about 63,239 (293)
Forkhead Box O transcription factors: Key players in redox signaling
, 2011 The Forkhead Box O (FOXO) transcription factors are famous for their role in longevity: both Caenorhabditis elegans and Drosophila melanogaster can extend their median and maximum lifespan in a FOXO-dependent manner, and certain single nucleotide ...
Dansen, Tobias B.
core
The FASEB Journal, Volume 40, Issue 13, 15 July 2026.Simvastatin induces metabolic suppression, mitochondrial dysfunction, and atrophy‐related responses in skeletal muscle cells. In differentiated C2C12 myotubes, metformin partially attenuates these alterations by preserving myotube structural integrity, reducing cellular stress signaling, and maintaining mitochondrial network organization despite ...
Chuqi He +6 more
wiley +1 more source
Genome-wide binding studies reveal DNA binding specificity mechanisms and functional interplay amongst Forkhead transcription factors. [PDF]
Nucleic Acids Res, 2016 Chen X, Ji Z, Webber A, Sharrocks AD.
europepmc +1 more source
Structure=function relationships underlying regulation of FOXO transcription factors.
, 2008 The FOXO subgroup of forkhead transcription factors plays a central role in cell-cycle control, differentiation, metabolism control, stress response and apoptosis. Therefore, the function of these important molecules is tightly controlled by a wide range
V Obsilova, T Obsil
core
Endocrinology, Diabetes &Metabolism, Volume 9, Issue 4, July 2026.This article systematically reviews how insulin resistance (IR) disrupts endometrial receptivity by interfering with glucose metabolism mechanisms, ultimately leading to infertility in patients with Polycystic Ovary Syndrome (PCOS). ABSTRACT Introduction Insulin resistance (IR) is one of the important pathologic bases of polycystic ovary syndrome (PCOS)
Si‐yan Huang +7 more
wiley +1 more source
European Journal of Pain, Volume 30, Issue 6, July 2026.ABSTRACT Background Fibromyalgia is a syndrome characterised by widespread chronic pain, which is believed to be mediated by a state of central sensitisation (CS). Based on the hypothesis that CS itself could have genetic determinants, our aim was to further explore this pathway.
Nicolas Macian +8 more
wiley +1 more source
Health Science Reports, Volume 9, Issue 7, July 2026.ABSTRACT Introduction Alopecia areata (AA) is an autoimmune disorder characterized by hair loss due to immune‐mediated destruction of hair follicles. The polygenic nature of AA, influenced by genetic and environmental factors, complicates its pathogenesis.
Ahmed Ibrahim AbdElneam +4 more
wiley +1 more source
Manufacturing and clinical applications of non‐CAR‐T immune effector cells
Transfusion, EarlyView.
Thane Kubik +2 more
wiley +1 more source
Urologic Bacteriome: The Hero or the Villain in Prostate Cancer Onset, Progression, and Treatment?
Medicinal Research Reviews, Volume 46, Issue 4, Page 1111-1151, July 2026.ABSTRACT Prostate cancer (PCa) is the second most frequently diagnosed cancer in men worldwide and the fifth leading cause of cancer‐related mortality, presenting urgent unmet clinical needs in diagnosis and treatment. The recognition of the microbiome as a key factor in human health has prompted numerous studies, revealing an exciting new approach to ...
Lara R. S. Fonseca +6 more
wiley +1 more source
Loss of Interdependent Binding by the FoxO1 and FoxA1/A2 Forkhead Transcription Factors Culminates in Perturbation of Active Chromatin Marks and Binding of Transcriptional Regulators at Insulin-sensitive Genes. [PDF]
J Biol Chem, 2016 Yalley A +4 more
europepmc +1 more source