Results 211 to 220 of about 94,249 (285)

Regulation of the Growth-Inhibitory Activity of Fhl1 via Interaction With Ifh1 and Crf1 at the Ribosomal Protein Gene Promoters in Saccharomyces cerevisiae. [PDF]

Genes Cells
Shimamura N, Kasahara K.
europepmc   +1 more source

Forkhead Transcription Factors: Key Players in Development and Metabolism

Developmental Biology, 2002
Carlsson, Peter, Mahlapuu, Margit
openaire   +2 more sources

The Evolving Therapeutic Landscape of Gallic Acid: A Review of Mechanistic Insights and Clinical Potential

Molecular Nutrition &Food Research, Volume 70, Issue 9, 13 May 2026.
ABSTRACT Gallic acid (GA), a plant‐derived phenolic compound, is evolving from a general antioxidant into a specific molecular modulator and a functional building block for advanced biomedical materials. This review synthesizes recent insights underpinned by GA's “redox duality”—its capacity to act as either a radical scavenger or a pro‐oxidant.
Woo Hyun Park
wiley   +1 more source

From flower buds to bolls: how cotton reproductive structures shape boll weevil development, reproduction and survival

Pest Management Science, Volume 82, Issue 5, Page 4576-4584, May 2026.
Female boll weevils feeding on flower buds promote reproduction regardless of their immature diet, whereas boll feeding increases lipid reserves and lifespan, revealing a nutrition‐driven trade‐off that sustains survival and reproduction in tropical boll weevil populations.
Roberta Ramos Coelho, Guilherme Gomes Rolim, Franklin Magliano da Cunha, Valéria Wanderley‐Teixeira, José Dijair Antonino, Jorge Braz Torres   +5 more
wiley   +1 more source

The future of Forkhead box O transcription factors. [PDF]

Biochem J
Huang H, Gui T, Burgering BM.
europepmc   +1 more source

Epigenetic Dysregulation of the NKX2‐1/SPDEF Axis Drives Persistent Goblet Cell Differentiation and Epithelial Barrier Dysfunction in Chronic Obstructive Pulmonary Disease

Respirology, Volume 31, Issue 5, Page 484-497, May 2026.
This study investigated airway epithelial barrier dysfunction persistence in ex‐smokers with COPD and underlying mechanisms using single‐cell RNA and ATAC sequencing. Epigenetic NKX2‐1/SPDEF dysregulation maintains goblet cell hyperplasia and barrier dysfunction despite long‐term smoking cessation.
Ayaka Shiota, Keiko Kan‐o, Yumiko Ishii, Tomoaki Koga, Takeshi Sawada, Kei‐ichiro Yasunaga, Shingo Usuki, Tatsuya Katsuno, Shigesato Inoue, Tomohiro Ogawa, Akihiro Jo, Satoru Fukuyama, Mitsuyoshi Nakao, Hiroaki Ogata, Mizuho A. Kido, Sachiko Tsukita, Koichiro Matsumoto, Isamu Okamoto   +17 more
wiley   +1 more source

Vitamin K2 Extends Lifespan by Alleviating Mitochondrial Stress via the JNK‐1/SIR‐2.1/DAF‐16 Signaling Axis in Caenorhabditis elegans

Aging Cell, Volume 25, Issue 5, May 2026.
Vitamin K2 activates the JNK‐1/SIR‐2.1/DAF‐16 signaling axis in C. elegans, alleviating mitochondrial stress, reducing ROS accumulation, preserving mitochondrial function, and extending lifespan. These findings reveal a novel anti‐aging mechanism of Vitamin K2 through mitochondrial protection and stress resistance enhancement.
Song‐Yu Guo, Yu‐Qi Li, Hua Piao, Wen‐Fei Zheng, Si‐Qi Li, Ze‐Yang Liu, Jun‐Ting Lv, Yue Kong, Qi‐Fa Li, Ying‐Zi Wang, Shu‐Zhuang Li, Chun‐Li Zhao, Shao Li   +12 more
wiley   +1 more source

Intragenic loss-of-function variants in transcription factors <i>MAZ</i>, <i>FOXP1</i> and <i>SIN3B</i> in colobomatous microphthalmia. [PDF]

J Med Genet
Seese SE, Reis LM, Schneider A, Bardakjian T, Semina EV.   +4 more
europepmc   +1 more source

Club Cells in Nasal Epithelial Repair: Insights From an IL‐13‐Induced Inflammatory Model

Allergy, Volume 81, Issue 5, Page 1459-1471, May 2026.
Four inflammatory endotypes of CRSwNP, defined by eosinophil and neutrophil infiltration, show distinct patterns of basal, club, ciliated, and goblet cell expression in nasal epithelium. Using an ALI‐HNECs model, we demonstrate that IL‐13 impairs mucociliary function by promoting club‐to‐goblet cell differentiation while inhibiting club‐to‐ciliated ...
Zhi‐Qun Huang, Jing Liu, Jing Ye, Li‐Ying Sun, Hsiao Hui Ong, Yang Peng, Bing‐Qi Lin, Jun‐Hao Tu, Ke‐Shuang Wang, Yi‐Shan Xiong, Qing Luo, Mark Thong, Yu Xu, De‐Yun Wang   +13 more
wiley   +1 more source

Ubiquitin-specific protease 5 promotes breast cancer progression by stabilizing Forkhead box M1 through deubiquitination. [PDF]

Cytojournal
Wang X, Chen T, Wu S, Wu Y.
europepmc   +1 more source