Results 171 to 180 of about 216,058 (206)

JNK regulates lifespan in Caenorhabditis elegans by modulating nuclear translocation of forkhead transcription factor/DAF-16

open access: green, 2005
Seung Wook Oh   +5 more
openalex   +1 more source

Atypical MAPKs in cancer

open access: yesThe FEBS Journal, Volume 292, Issue 9, Page 2173-2188, May 2025.
Mitogen‐activated protein kinases (MAPKs) regulate various cellular processes, including proliferation, differentiation, and motility. Alterations in these signalling pathways can lead to various diseases, including cancer. The atypical MAPKs ERK3 (MAPK6), ERK4 (MAPK4), ERK7/8 (MAPK15) and NLK have long been neglected in kinomic studies.
Katrin Dahm   +4 more
wiley   +1 more source

Discovery of a novel alpha isoform of the long‐known enzyme LDHA provides new insights into cancer research

open access: yesThe FEBS Journal, Volume 292, Issue 9, Page 2219-2222, May 2025.
Lactate dehydrogenase A is a key enzyme in energy metabolism, with significant roles in cancer progression. Huang et al. identified LDHAα, a novel LDHA isoform derived from an alternative transcript initiated at AUG198, producing a protein 3 kDa larger than canonical LDHA. LDHAα exhibits enhanced glycolytic activity and promotes glucose uptake, lactate
Wonyoung Park   +3 more
wiley   +1 more source

Are SNPs Linked to Somatic Cell Score Suitable Markers for the Susceptibility to Specific Mastitis Pathogens in Holstein Cows?

open access: yesJournal of Animal Breeding and Genetics, Volume 142, Issue 3, Page 354-361, May 2025.
ABSTRACT Mastitis in cattle is often caused by microorganism infections in the udder. The three most common pathogens are esculin‐positive streptococci (SC+), coagulase‐negative staphylococci (CNS), and Escherichia coli (E. coli). In a previous study, 10 SNPs were associated with somatic cell score and mastitis in diverse Holstein populations.
U. Müller   +6 more
wiley   +1 more source

DNA methyltransferase 1/miR-342-3p/Forkhead box M1 signaling axis promotes self-renewal in cervical cancer stem-like cells <i>in vitro</i> and nude mice models. [PDF]

open access: yesWorld J Stem Cells
Cao XZ   +11 more
europepmc   +1 more source

Forkhead transcription factors and cardiovascular biology. [PDF]

open access: yesCirc Res, 2008
Papanicolaou KN, Izumiya Y, Walsh K.
europepmc   +1 more source

Surviving on Limited Resources: Effects of Caloric Restriction on Growth, Gene Expression and Gut Microbiota in a Species With Male Pregnancy (Hippocampus erectus)

open access: yesMolecular Ecology, Volume 34, Issue 9, May 2025.
ABSTRACT Caloric restriction (CR) studies have traditionally focused on species with conventional reproductive roles, emphasising female's greater investment in costly gametes and parental care. While the divergent impact of CR on males and females is evident across species, the factors driving this variation, that is, resource allocation to ...
Freya Adele Pappert   +3 more
wiley   +1 more source

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