Results 41 to 50 of about 771,287 (219)
La formation professionnelle à distance à la lumière des organisations capacitantes
Distances et Médiations des Savoirs, 2016 Professional training is concerned by the digitalization of enterprises, a process which refers to the massive use of new technologies. After the popularity of e-learning, the environments inspired by the academic MOOC (COOC, SPOC etc.) appeared to many ...
Anca Boboc, Jean-Luc Metzger
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Bilan de pratiques évaluatives des apprentissages à distance en contexte de formation universitaire
Revue Internationale de Pédagogie de l’Enseignement Supérieur, 2016 The development of distance learning in higher education raises the question of the nature and validity of evaluation practices of teachers in a context where the nature of the collected data, the scope and credibility of their interpretation and the ...
Isabelle Nizet +4 more
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Formation à distance et activité du stagiaire de la formation professionnelle continue
Éducation et Socialisation, 2014 This paper discusses the practical vocational training in the framework of a hybrid system. This is particularly ask the vocationnal education training as operational content to facilitate the transformation of subjects in action.
Béatrice Verquin-Savarieau
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FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Analyse de Penser la mise à distance en formation
ALSIC: Apprentissage des Langues et Systèmes d'Information et de Communication, 2000 This article reviews a book or document.
Anne-Laure Foucher
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Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Formation à distance sur la communication scientifique par affiche
Médiations & Médiatisations, 2019 La formation à distance constitue une pratique encore nouvelle pour plusieurs acteurs de l’enseignement universitaire. Des bibliothécaires universitaires éprouvent depuis quatre ans une formation à distance sur la communication scientifique par affiche ...
Catherine Seguin, Michel Courcelles
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