Results 101 to 110 of about 2,239,947 (297)

Le non-recours à la formation continue en entreprise

La Nouvelle Revue du Travail
This article seeks to show that, although the notion of non-take up was developed in the context of the fight against poverty, it is relevant for understanding the relationship of employees to in-company training. While successive reforms of training law
Emmanuel de Lescure
doaj   +1 more source

Les barrières à une bonne prise en charge des diabétiques dans les structures de première ligne de la province de Khouribga (MAROC)

The Pan African Medical Journal, 2012
INTRODUCTION: Le diabète constitue un important enjeu de santé publique au Maroc et représente un défi auquel les médecins généralistes sont confrontés dans leur pratique quotidienne.
Samira Hassoune, Soufiane Badri, Samira Nani, Leila Belhadi, Abderrahmane Maaroufi   +4 more
doaj   +1 more source

Optimiser la communication et l'image de la formation continue de la HEG [PDF]

, 2014
Dans le monde actuel, où la concurrence est féroce et l’offre est abondante, il est primordial pour les entreprises de réussir à se démarquer et d’attirer l’attention sur elles.
Hovorkova, Michaella, Tesnier, Grégory
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Valorisation salariale de la formation continue en France et en Allemagne

, 1998
Document séminaire LESTLes raisons mêmes de la formation professionnelle continue (fpc) et ses formes de valorisation salariale sont largement dépendantes de la manière dont sont construits les rapports entre formation initiale et marché du travail.
Béret, Pierre, Dupray, Arnaud
core   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

PAIRFORM@NCE : UN DISPOSITIF HYBRIDE POUR LA FORMATION CONTINUE DES ENSEIGNANTS

, 2007
We present the first results of a development-research concerning the design and the experimentation of a national blended learning device devoted to the in-service teacher training. The device is based on professional didactic and collaborative training
Bertrand, Claude
core   +1 more source