Results 111 to 120 of about 442,575 (310)

Secteur de formation 9 : électrotechnique

open access: yes, 2008
Titre de l'écran-titre (visionné le 21 août 2008)"Secteur de formation 9 ...
Huot, Benoit   +5 more
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Quels types de parcours de formation pour encourager le lifelong learning chez les enseignant-e-s? [PDF]

open access: yes
Cette présentation centre la discussion autour des forces et faiblesses de la création de parcours de formation continue (parcours thématiques ou par publics cibles) pour encourager le développement d’un état d’esprit de lifelong learning chez les ...
Paillard, Elodie
core  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Secteur de formation 2 : agriculture et pêches

open access: yes, 2009
Titre de l'écran-titre (visionné le 9 juillet 2009)"Secteur de formation 2 : agriculture et pêches"Version électronique d'un document imprimé publié en ...
Fons, Jean-Pierre   +3 more
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Questionner une égalité entre les sexes en formation continue : enjeux, dispositifs et perspectives de transformation

open access: yes
Notre présentation examine les rapports sociaux de sexe (Kergoat, 1992) dans le contexte de la formation continue en enseignement dans une Haute école suisse.
Tadlaoui-Brahmi, Ania, Moraes, Tauana
core  

La formation professionnelle continue des exploitants agricoles

open access: yes, 2016
ELBAUM Mireille, MAGNIER Antoine, GOSSET Georges, SIMON Jacques. La formation professionnelle continue des exploitants agricoles. Paris : Inspection générale des affaires sociales, déc. 2015, 291 p.
Rédaction
core  

Towards Understanding the Formation of Continuous IT Use.

open access: yes, 2013
The benefit of IT comes from the continuing use, not its initial adoption. Compared to the amount of research done on IT adoption, insights on why users continue to use IT systems are sparse. Nevertheless, there are publications with promising ideas and findings aiming to explain continuous use.
Gebauer, Lysann   +2 more
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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