Formyl peptide receptors from immune and vomeronasal system exhibit distinct agonist properties. [PDF]
Bufe B, Schumann T, Zufall F.
europepmc +1 more source
Human neutrophils recognize group B streptococci <i>via</i> formylated peptide receptors and toll-like receptor 8. [PDF]
Fiore L +11 more
europepmc +1 more source
N-terminal formylmethionine as a degron and a specific signal in proteostasis and stress adaptation. [PDF]
Lee CS, Kim D, Hwang CS.
europepmc +1 more source
From data to discovery: The rise of information-theoretic predictive models in drug development. [PDF]
Saied H +5 more
europepmc +1 more source
uPAR/suPAR Signaling and Organ Crosstalk in Cardiovascular-Kidney-Metabolic Syndrome. [PDF]
Hayek SS, Dryer SE.
europepmc +1 more source
Tumor suppressor function of formyl peptide receptor 1 in gastrointestinal cancers: a focus on the underlying signaling. [PDF]
Marotta M +3 more
europepmc +1 more source
LAT1/SLC7A5-mediated amino acid uptake is regulated by redox signals triggered by formyl-peptide receptor 2. [PDF]
Cassese M +5 more
europepmc +1 more source
Integrated pro-resolving mechanisms: a new dimension for optimizing anti-inflammatory therapy in asthma - a review of impaired inflammation resolution in airway remodeling. [PDF]
Zhang B +5 more
europepmc +1 more source
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Formyl-peptide receptors revisited
Trends in Immunology, 2002Leukocytes accumulate at sites of inflammation and microbial infection in direct response to locally produced chemotactic factors, which signal through specific G protein-coupled receptors. The first chemotactic factors to be structurally defined were the N-formyl peptides. Unlike other leukocyte chemoattractants, N-formyl peptides could originate from
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Role of Formyl Peptide Receptors in Gastrointestinal Healing
Current Pharmaceutical Design, 2018The wound healing and the barrier restoration of the gastrointestinal (GI) mucosa must be continuously ensured to allow homeostasis of the gastrointestinal tract and of all the surrounding tissues. Several lines of the evidence report a key role of innate immunity, and in particular of Pattern Recognition Receptors (PRRs), in controlling the ...
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