Results 61 to 70 of about 116,815 (334)

ACSS2‐Mediated Histone H4 Lysine 12 Crotonylation (H4K12cr) Alleviates Colitis via Enhancing Transcription of CLDN7

Advanced Science, EarlyView.
Histone lysine crotonylation (Kcr) is a highly conserved posttranslational modification implicated with crucial biological processes. This study reveals that ACSS2‐mediated H4K12cr upregulated CLDN7 transcription to strengthen intestinal epithelial barrier.
Ming Yuan, Shaopeng Chen, Zhensen Lin, Runfeng Yu, Kang Chao, Shubiao Ye, Qing Li, Haoxian Ke, Chi Zhang, Junfeng Huang, Guanzhan Liang, Tuo Hu, Xiang Gao, Ping Lan, Xianrui Wu   +14 more
wiley   +1 more source

Exploring food fortification potential of neglected legume and oil seed crops for improving food and nutrition security among smallholder farming communities: A systematic review

Journal of Agriculture and Food Research, 2021
A systematic review of literature on value-addition and food fortification of cereals using neglected legume and oil seed crops among smallholder farming communities was done.
Marongwe F. Desire, Masamha Blessing, Nyakudya Elijah, Mandumbu Ronald, Kamota Agather, Zengeza Tapiwa, Mapfeka R. Florence, Nyamadzawo George   +7 more
doaj  

A Super‐Enhancer‐Driven Transcriptional Regulatory Circuit Underlying Abiraterone Resistance in Castration‐Resistant Prostate Cancer

Advanced Science, EarlyView.
This study identifies a super‐enhancer‐driven transcriptional regulatory circuit comprising BCL6, SMAD3, and NFIB that cooperate to drive cholesterol synthesis via SREBF2/HMGCR/FDFT1 activation and regulate CDK2/CCND3 for cell cycle control. Targeting this circuit with BI‐3802 or downstream inhibitors (Fatostatin/Lovastatin) overcomes abiraterone ...
Liling Jiang, Jiamin Wang, Guanjie Peng, Haichuan Zhang, Jinxin Fang, Yingyin Gao, Enzhe Lou, Yangzhou Liu, Wa Ding, Bingyuan Liu, Qiong Mao, Lizhen Jiang, Aochu Liu, Xinyue Li, Shiwen Hu, Qiaomin Ma, Yueyuan Zheng, Zhigang Zhao, Xianping Shi   +18 more
wiley   +1 more source

Food fortification strategies to deliver nutrients for the management of iron deficiency anaemia

Current Research in Food Science, 2022
A rising trend in the global prevalence of anaemia is still prevailing. To combat micronutrient deficiencies, World Health Organisation/Food Agriculture Organisation (2006) guidelines recommended four chief strategies – supplementation, fortification ...
Naman Kaur, Aparna Agarwal, Manisha Sabharwal   +2 more
doaj  

Fortificaţia de la Ungra. Cercetări magnetometrice recente [PDF]

Cercetări Arheologice
The fortification of Ungra is one of the points of interest for the archaeology of the first centuries AD in Brașov County. The archaeological site is located at the intersection of two communication routes, the Homoroade Valley and the Gorge of the Olt ...
Alexandru Popa, Silviu Gridan, Andrea Popa   +2 more
doaj   +1 more source

Reducing the burden of iron deficiency anemia in Cote D’Ivoire through fortification

Journal of Health, Population and Nutrition, 2020
Background Iron deficiency anemia (IDA) is highly prevalent in the Cote d’Ivoire and has severe health and economic consequences. In this paper, we apply a health economic model to quantify the burden of IDA, and the contribution of nationwide mandatory ...
Alberto Prieto-Patron, Zsuzsa V. Hutton, Giovanni Fattore, Magalie Sabatier, Patrick Detzel   +4 more
doaj   +1 more source

The nutritional impact of fortified ready-to-eat cereals on the diets of school age children [PDF]

, 2000
Includes bibliographical ...
Johnson, Carolyn
core  

Parallel repetition via fortification: analytic view and the quantum case [PDF]

, 2016
In a recent work, Moshkovitz [FOCS'14] presented a transformation n two-player games called "fortification", and gave an elementary proof of an (exponential decay) parallel repetition theorem for fortified two-player projection games.
Bavarian, Mohammad, Vidick, Thomas, Yuen, Henry   +2 more
core   +3 more sources

Piezo1 Activation Improves NSCLC Liver Metastasis Immunotherapy by Overriding Matrix Stiffness‐Mediated Bimodal PD‐L1/CXCL10 Regulation

Advanced Science, EarlyView.
This study demonstrates that Piezo1 activation enhances FAK‐YAP‐mediated upregulation of PD‐L1 and CXCL10, thereby promoting an immunotherapy‐responsive tumor microenvironment in NSCLC. Cyclic stretch modulates the PD‐L1/CXCL10 response to ECM stiffness, reshaping their expression dynamics.
Tian Zhang, Yuan Li, Bo Cheng, Zhao Xu, Mengjie Liu, Jinteng Feng, Yixue Bai, Yang Yu, Panpan Jiang, Luying Geng, Feng Xu, Hui Guo   +11 more
wiley   +1 more source

Thermal compaction as an alternative approach for full-RAP base layer construction

Scientific Reports
The use of Reclaimed Asphalt Pavement (RAP) in road base layers represents a solution to reduce the consumption of natural aggregates. However, the variability of RAP properties poses challenges to its application, particularly regarding mechanical ...
Lisley Madeira Coelho, Belayne Zanini Marchi, Pedro Henrique Poubel Mendonça da Silveira, Afonso Rangel Garcez de Azevedo, Sergio Neves Monteiro, Antônio Carlos Rodrigues Guimarães   +5 more
doaj   +1 more source