Results 31 to 40 of about 36,369 (248)

Resistance to fosfomycin is increasing and is significantly associated with extended-spectrum β-lactamase-production in urinary isolates of Escherichia coli

Medical Microbiology and Immmunology, 2022
Fosfomycin has become a therapeutic option in urinary tract infections. Our objective was to evaluate the in vitro activity of fosfomycin against Escherichia coli isolated from urine samples in 2013, 2018 and 2021.
E. Ríos, María Del Carmen López Diaz, E. Culebras, I. Rodríguez-Avial, C. Rodríguez-Avial   +4 more
semanticscholar   +1 more source

Synergistic Effect of Cefazolin Plus Fosfomycin Against Staphylococcus aureus in vitro and in vivo in an Experimental Galleria mellonella Model

Frontiers in Pharmacology, 2021
Objectives: This study investigated the synergistic in vitro and in vivo activity of cefazolin plus fosfomycin against methicillin-susceptible and methicillin-resistant S.
Manuel Kussmann, Markus Obermueller, Matthias Karer, Matthias Karer, Richard Kriz, Rui-Yang Chen, Lena Hohl, Lisa Schneider, Heinz Burgmann, Ludwig Traby, Matthias G. Vossen   +10 more
doaj   +1 more source

Oral Fosfomycin Formulation in Bacterial Prostatitis: New Role for an Old Molecule-Brief Literature Review and Clinical Considerations

Infectious Disease Reports, 2022
Bacterial prostatitis infections are described as infections that are difficult-to-treat, due to prostate anatomic characteristics along with clinical difficulty in terms of diagnosis and management. Furthermore, the emergence of multidrug resistant (MDR)
Andrea Marino, S. Stracquadanio, Carlo Maria Bellanca, Egle Augello, Manuela Ceccarelli, G. Cantarella, R. Bernardini, G. Nunnari, B. Cacopardo   +8 more
semanticscholar   +1 more source

In vitro activity of fosfomycin against Campylobacter isolates from poultry and wild birds. [PDF]

PLoS ONE, 2018
Fosfomycin is a broad-spectrum antibiotic with the activity against both Gram-positive and Gram-negative pathogens by inhibiting the bacterial cell wall synthesis. Given the potential therapeutic efficacy of fosfomycin against Campylobacter spp., the aim
Bai Wei, Min Kang
doaj   +1 more source

Successful Treatment of Acute Prostatitis Caused by Multidrug-Resistant Escherichia coli With Tigecycline Monotherapy [PDF]

, 2020
We present a successful treatment, with tigecycline monotherapy, of acute prostatitis caused by multidrug-resistant Escherichia coli harboring an NDM-1 carbapemenase along with a CMY-2 cephalosporinase and a TEM ...
Babouee Flury, Baharak, Buetti, Niccolo, Casanova, Carlo, Furrer, Hansjakob, Jent, Philipp, Livermore, David M, Lo Priore, Elia, Pelzer, Niklas   +7 more
core   +2 more sources

In Vitro and In Vivo Studies of Oritavancin and Fosfomycin Synergism against Vancomycin-Resistant Enterococcus faecium

Antibiotics, 2022
Therapeutic options for infections caused by vancomycin-resistant enterococci are currently suboptimal. Combination regimens where fosfomycin is used alongside existing treatments are emerging given the proven synergistic potential and PK/PD properties ...
C. Lagatolla, J. Mehat, R. L. La Ragione, R. Luzzati, Stefano Di Bella   +4 more
semanticscholar   +1 more source

Molecular mechanisms and epidemiology of fosfomycin resistance in enterococci isolated from patients at a teaching hospital in China, 2013–2016

Journal of Global Antimicrobial Resistance, 2020
Objectives: The aim of this study was to investigate the mechanisms of fosfomycin resistance and epidemiological characteristics in fosfomycin-resistant enterococci in China.
Xiucai Zhang, Wenzi Bi, Lijiang Chen, Yizhi Zhang, Renchi Fang, Jianming Cao, Tieli Zhou   +6 more
doaj   +1 more source

Synergistic Activity of Fosfomycin, Ciprofloxacin, and Gentamicin Against Escherichia coli and Pseudomonas aeruginosa Biofilms [PDF]

, 2019
Gram-negative (GN) rods cause about 10% periprosthetic joint infection (PJI) and represent an increasing challenge due to emergence of antimicrobial resistance.
Di Luca, Mariagrazia, Gonzalez Moreno, Mercedes, Tkhilaishvili, Tamta, Trampuz, Andrej, Wang, Lei   +4 more
core   +1 more source

The novel fosfomycin resistance gene fosY is present on a genomic island in CC1 methicillin-resistant Staphylococcus aureus

Emerging Microbes and Infections, 2022
Fosfomycin has gained attention as a combination therapy for methicillin-resistant Staphylococcus aureus infections. Hence, the detection of novel fosfomycin-resistance mechanisms in S. aureus is important.
Yiyi Chen, S. Ji, Lu Sun, Hai-ping Wang, Feiteng Zhu, Mengzhen Chen, Hemu Zhuang, Zhengan Wang, Shengnan Jiang, Yunsong Yu, Yan Chen   +10 more
semanticscholar   +1 more source

Synergistic activity of fosfomycin–meropenem and fosfomycin–colistin against carbapenem resistant Klebsiella pneumoniae: an in vitro evidence

Future Science OA, 2020
Aim: To evaluate the antibacterial activity of fosfomycin–meropenem and fosfomycin–colistin combinations against carbapenem-resistant Klebsiella pneumoniae (CR-Kp). Methods: A total of 50 CR-Kp isolates recovered from blood cultures were included in this
Yamuna Devi Bakthavatchalam, Abirami Shankar, Dhiviya Prabaa Muthuirulandi Sethuvel, Kalaiarasi Asokan, Kalaiarasi Kanthan, Balaji Veeraraghavan   +5 more
doaj   +1 more source