Results 41 to 50 of about 36,369 (248)
Clinical Infectious Diseases, 2020 Background We aimed to determine whether daptomycin plus fosfomycin provides higher treatment success than daptomycin alone for methicillin-resistant Staphylococcus aureus (MRSA) bacteremia and endocarditis. Methods A randomized (1:1) phase 3 superiority,
M. Pujol +52 more
semanticscholar +1 more source
Pathogens, 2022 Multidrug resistance of bacteria has prompted intensive development work on new medicines, but also the search for effective options among the oldest antibiotics.
B. Kowalska-Krochmal +12 more
semanticscholar +1 more source
RSC Advances, 2022 A new easily separable core–shell Fe3O4/PVP/ZIF-8 nanostructure adsorbent was synthesized and then examined for removal of Fosfomycin antibiotic from synthetic pharmaceutical wastewater. The removal process of Fosfomycin was expressed through testing the
Mai O Abdelmigeed +2 more
semanticscholar +1 more source
Antimicrobial Resistance and Infection Control, 2020 Background Fosfomycin exhibits excellent in vitro activity against multidrug-resistant pathogens, including methicillin-resistant Staphylococcus aureus (MRSA).
Yi-Chien Lee +3 more
doaj +1 more source
Assessing the emergence of resistance: the absence of biological cost in vivo may compromise fosfomycin treatments for P. aeruginosa infections. [PDF]
PLoS ONE, 2010 BACKGROUND: Fosfomycin is a cell wall inhibitor used efficiently to treat uncomplicated urinary tract and gastrointestinal infections. A very convenient feature of fosfomycin, among others, is that although the expected frequency of resistant mutants is ...
Alexandro Rodríguez-Rojas +6 more
doaj +1 more source
Multi-drug resistant Gram-negative bacteria: antibiotic-resistance and new treatment strategies [PDF]
, 2017 In this editorial, we treat the multi-drug-resistance of microorganisms such as Klebsiella pneumonia (Kp) and Acinetobacter baumanii and the issues concerning the management of these infections.
Angelis, Massimiliano De +2 more
core +1 more source
The potential negative impact of antibiotic pack on antibiotic stewardship in primary care in Switzerland: a modelling study. [PDF]
, 2020 BACKGROUND: In Switzerland, oral antibiotics are dispensed in packs rather than by exact pill-count. We investigated whether available packs support compliance with recommended primary care treatment regimens for common infections in children and adults.
Berger, C +5 more
core +3 more sources
Mechanisms of high-level fosfomycin resistance in Staphylococcus aureus epidemic lineage ST5
Journal of Antimicrobial Chemotherapy, 2022 Objectives Fosfomycin resistance has become a clinical concern. In this study, we analysed the dynamic change of fosfomycin MIC in the epidemic Staphylococcus aureus lineages in a teaching hospital in Shanghai for 12 years and sought to elucidate the ...
Tianchi Chen +9 more
semanticscholar +1 more source
Intracellular Concentrations of Fosfomycin in Alveolar Macrophages from Weaning Piglets [PDF]
, 2015 At weaning, piglets are more susceptible to infectious diseases, being respiratory syndromes one of the most frequent conditions. Fosfomycin is indicated for the treatment of a variety of porcine bacterial pathogens, with MIC90 ranging between 0.25-0.50 ...
Dieguez, Susana Nelly +6 more
core +2 more sources
Archives of Disease in Childhood, 2022 Objective To assess pharmacokinetics and changes to sodium levels in addition to adverse events (AEs) associated with fosfomycin among neonates with clinical sepsis. Design A single-centre open-label randomised controlled trial.
C. Obiero +15 more
semanticscholar +1 more source