Results 51 to 60 of about 36,369 (248)

The fosfomycin resistance gene fosB3 is located on a transferable, extrachromosomal circular intermediate in clinical Enterococcus faecium isolates. [PDF]

PLoS ONE, 2013
Some VanM-type vancomycin-resistant Enterococcus faecium isolates from China are also resistant to fosfomycin. To investigate the mechanism of fosfomycin resistance in these clinical isolates, antimicrobial susceptibility testing, filter-mating, Illumina/
Xiaogang Xu, Chunhui Chen, Dongfang Lin, Qinglan Guo, Fupin Hu, Demei Zhu, Guanghui Li, Minggui Wang   +7 more
doaj   +1 more source

Enterococcal periprosthetic joint infection: clinical and microbiological findings from an 8-year retrospective cohort study [PDF]

, 2019
BACKGROUND: Treatment of enterococcal periprosthetic joint infections (PJI) is challenging due to non-standardized management strategies and lack of biofilm-active antibiotics. The optimal surgical and antimicrobial therapy are unknown.
Akgün, Doruk, Perka, Carsten, Renz, Nora, Trampuz, Andrej, Trebse, Rihard   +4 more
core   +1 more source

Optimal management of urinary tract infections in older people [PDF]

, 2011
Urinary tract infections (UTI) occur frequently in older people. Unfortunately, UTI is commonly overdiagnosed and overtreated on the basis of nonspecific clinical signs and symptoms.
Beveridge, Louise A., Davey, Peter G., McMurdo, Marion E. T., Phillips, Gabby   +3 more
core   +4 more sources

Mechanisms of fosfomycin resistance in clinical isolates of carbapenem-resistant Klebsiella pneumoniae

Journal of Global Antimicrobial Resistance, 2020
Objectives: Older antimicrobials such as fosfomycin are being considered as alternative agents in the treatment of drug-resistant organisms. However, there are limited data on the usefulness of fosfomycin against carbapenem-resistant Klebsiella ...
Peng Liu, Shuo Chen, Zhuo-ying Wu, Meng Qi, Xiang-yang Li, Cai-xia Liu   +5 more
doaj   +1 more source

Biofilm is a major virulence determinant in bacterial colonization of chronic skin ulcers independently from the multidrug resistant phenotype [PDF]

, 2017
Bacterial biofilm is a major factor in delayed wound healing and high levels of biofilm production have been repeatedly described in multidrug resistant organisms (MDROs).
Bordignon, Valentina, Cavallo, Ilaria, Cilli, Laura, De Santis, Alessandra, Di Domenico, Enea Gino, Di Salvo, Fabiola, Ensoli, Fabrizio, Farulla, Ilaria, Gallo, Maria Teresa, La Parola, Ilaria Lesnoni, Pimpinelli, Fulvia, Pontone, Martina, Prignano, Grazia, Sperduti, Isabella, Toma, Luigi, Vespaziani, Matteo   +15 more
core   +2 more sources

Multicenter Evaluation of the Novel ETEST Fosfomycin for Antimicrobial Susceptibility Testing of Enterobacterales, Enterococcus faecalis, and Staphylococcus Species

Journal of Clinical Microbiology, 2022
Fosfomycin is a phosphonic acid derivative active against a wide spectrum of Gram-positive and Gram-negative pathogens. It is used for the treatment of uncomplicated urinary tract infections (uUTI) or severe infections by oral or intravenous (i.v ...
A. Goer, L. Blanchard, A. van Belkum, K. Loftus, T. Armstrong, S. Gatermann, D. Shortridge, B. J. Olson, J. Meece, T. Fritsche, M. Pompilio, D. Halimi, C. Franceschi   +12 more
semanticscholar   +1 more source

Presence of New Delhi metallo-β-lactamase gene (NDM-1) in a clinical isolate of Acinetobacter junii in Argentina [PDF]

, 2016
Here we report the presence of a clinically significant A. junii blaNDM-1 positive in a 38-year-old woman who was admitted to the emergency department with a fever and leg ulcers with signs of infection.
Almuzara, Marisa, Barberis, Claudia, Cittadini, Roxana, Del Castillo M,, Lazzaro, T., Montaña, Sabrina Daiana, Ramírez, M. S., Uong, S., Vay, Carlos Alberto   +8 more
core   +1 more source

Fosfomycin Susceptibility Testing Using Commercial Agar Dilution Test

Microbiology spectrum, 2022
Fosfomycin is increasingly needed to treat infection due to multidrug resistant microorganisms. Yet, the antimicrobial susceptibility test (AST) of fosfomycin is fraught with difficulties or often laborious to perform.
P. Croughs, Michelle Konijnendijk-de Regt, E. Yusuf   +2 more
semanticscholar   +1 more source

Prevalence of fosfomycin resistance and mutations in murA, glpT, and uhpT in methicillin-resistant Staphylococcus aureus strains isolated from blood and cerebrospinal fluid samples

Frontiers in Microbiology, 2016
In China, fosfomycin alone or in combination with other antibiotics is commonly used in the treatment of infections caused by Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). Although fosfomycin-resistant S.
Zhuyingjie eFu, Ying eMa, Chunhui eChen, Yan eGuo, Fupin eHu, Yang eLiu, Xiaogang eXu, Minggui eWang   +7 more
doaj   +1 more source

Pharmacodynamics of Linezolid Plus Fosfomycin Against Vancomycin–Resistant Enterococcus faecium in a Hollow Fiber Infection Model

Frontiers in Microbiology, 2021
The optimal therapy for severe infections caused by vancomycin-resistant Enterococcus faecium (VREfm) remains unclear, but the combination of linezolid and fosfomycin may be a good choice.
Shuaishuai Wang, Shuaishuai Wang, Huiping Liu, Huiping Liu, Jun Mao, Jun Mao, Yu Peng, Yu Peng, Yisong Yan, Yisong Yan, Yaowen Li, Yaowen Li, Na Zhang, Na Zhang, Lifang Jiang, Lifang Jiang, Yanyan Liu, Jiabin Li, Xiaohui Huang, Xiaohui Huang   +19 more
doaj   +1 more source