Results 171 to 180 of about 106,447 (316)

A Programmable Nanoreactor Orchestrates Cascade of DNA Sensing to Amplify cGAS‐STING Activation for Cancer Immunotherapy

Advanced Science, EarlyView.
A programmable nanoreactor was engineered for precise cGAS‐STING pathway activation in cancer immunotherapy. This strategy bridges targeted tumor DNA damage with DC immunomodulation, providing a translatable platform to unlock innate and adaptive antitumor immunity.
Shuang Liang, Yiwei Tian, Feiyu Zhao, Yue Han, Kongshuo Ma, Linna Hai, Kaiqing Yun, Yueyang Zhao, Siqi Zhang, Ziyi Zhang, Yuxuan Peng, Kuan Hu, Jing Zhong, Bai Xiang, Zhaohui Wang   +14 more
wiley   +1 more source

Regulatory T cell dysfunction and immunotherapeutic breakthroughs in type 1 diabetes. [PDF]

Front Endocrinol (Lausanne)
Zhou KJ, Rong SJ, Liu YC, Sun F, Wang T, Yu QL, Wang CY.   +6 more
europepmc   +1 more source

Foxp3 and BATF cooperatively direct cis -regulatory programs and gene expression for functional differentiation of Treg cells [PDF]

Ryuichi Murakami, Norihito Hayatsu, Takahisa Miyao, Zhi Liu, S. Shibata, Masashi Matsuda, Yusuke Iizuka, Hideyuki Yoshida, Yoshinori Hasegawa, Wataru Ise, Haruhiko Koseki, Tomohiro Kurosaki, Shohei Hori   +12 more
openalex   +1 more source

Trojan Horse Strategy: How Biomimetic Nanomedicine Remodels the Tumor Microenvironment

Advanced Science, EarlyView.
This review focuses on biomimetic nanomedicines for tumor microenvironment (TME) remodeling, covering their diverse biomimetic types, design principles, and mechanisms of immune cell reprogramming and reversal of immunosuppressive microenvironments, with particular emphasis on their application in synergistic immunotherapy.
Wanrong Wang, Siqi Mu, Juan Zhang, Guisong Shan, Xueqian Li, Ran Wang, Tao Guo, Xiaoyan He   +7 more
wiley   +1 more source

FoxP3 forms a head-to-head dimer in vivo and stabilizes its multimerization on adjacent microsatellites. [PDF]

Cell Rep
Leng F, Clark R, Zhang W, Viennet T, Wang C, Arthanari H, Wang X, Hur S.   +7 more
europepmc   +1 more source

An Enzyme‐Like Catalyzed Nanosheets for Redox Stress Oscillation Therapy Against Bacterial Infections

Advanced Science, EarlyView.
Bacterial biofilms form a physicochemical barrier. Their dense network structure and redox homeostasis confer high resistance to antimicrobial treatments and immune‐mediated killing and clearance. In this study, SnSe nanosheets with enzyme‐like properties and piezoelectric catalysis can oscillate to regulate bacterial redox homeostasis and improve the ...
Min Ge, Zhao Guo, Zhiming Zhang, Lanlu Lu, Zesong Ruan, Tingwang Shi, Yunfeng Chen, Ju Huang, Chaoliang Tan, Han Lin   +9 more
wiley   +1 more source

Discovery of Seven ROS-Sensitive Immune Checkpoints and 46 Ligands Mediating Immune Suppression Through T cell-APC Networks. [PDF]

J Cancer
Han B, Xu K, Saaoud F, Hou Y, Shao Y, Lu Y, Jiang X, Zhao H, Wang H, Yang X.   +9 more
europepmc   +1 more source

FOXP3 wt Allele [PDF]

, 2020
openaire   +1 more source

The Scurfy mutation of FoxP3 in the thymus stroma leads to defective thymopoiesis [PDF]

, 2005
Xing Chang, Jian Gao, Qi Jiang, Jing Wen, Nick Seifers, Lishan Su, Virginia Godfrey, Tao Zuo, Pan Zheng, Yang Liu   +9 more
openalex   +1 more source

Supplementary Figure 1 from The Regulatory T Cell–Associated Transcription Factor FoxP3 Is Expressed by Tumor Cells

, 2023
Lisa M. Ebert, Bee Shin Tan, Judy Browning, Suzanne Svobodová, Sarah E. Russell, Naomi Kirkpatrick, Craig Gedye, Denis J. Moss, Sweet Ping Ng, Duncan MacGregor, Ian D. Davis, Jonathan Cebon, Weisan Chen   +12 more
openalex   +1 more source