Lack of Suppressive CD4+CD25+FOXP3+ T Cells in Advanced Stages of Primary Cutaneous T-Cell Lymphoma [PDF]
Machteld M. Tiemessen +5 more
openalex +1 more source
Abstract The diagnosis of T‐cell neoplasms remains one of the most challenging areas in hematopathology due to the immunophenotypic heterogeneity and subtle aberrancies often present in these entities. This “Best Practice” manuscript provides a practical framework for laboratories to design, validate, and interpret immunophenotyping studies of immature
Jean Oak +10 more
wiley +1 more source
HuR ablation destabilizes <i>Foxp3</i> mRNA and impairs regulatory T cell function, contributing to an autoimmune phenotype. [PDF]
Fattahi F +8 more
europepmc +1 more source
Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development [PDF]
Marc A. Gavin +9 more
openalex +1 more source
Structure of the forkhead domain of FOXP2 bound to DNA [PDF]
Bates, D. +7 more
core +2 more sources
RORγt‐APCs: The New Masters of Oral Tolerance
ABSTRACT Oral tolerance is defined by the hypo‐responsiveness of our body to fed antigens, and its failure can lead to immune‐mediated diseases, such as allergy, chronic inflammation and autoimmune diseases. Decades of research have demonstrated that antigen‐presenting cells (APCs) promote oral tolerance by inducing regulatory T cells (Tregs) and/or ...
Thierry Gauthier, WanJun Chen
wiley +1 more source
High IL-10 mRNA levels in regional lymph nodes of colon cancer patients indicate poor prognosis. [PDF]
Mohamed A +7 more
europepmc +1 more source
Tumor infiltrating Foxp3+ regulatory T‐cells are associated with recurrence in pathologic stage I NSCLC patients [PDF]
Rebecca P. Petersen +6 more
openalex +1 more source
Redefining the Skin Barrier: A Microbiome‐Integrated Multilayered Defense Model
ABSTRACT The skin constitutes a dynamic interface orchestrating a sophisticated multilayered defense system comprising physical, chemical, immune, and microbial barriers. This review synthesizes current understanding of the structural and functional integration of these barriers, emphasizing their synergistic interactions in maintaining cutaneous ...
Jingjing Xia +4 more
wiley +1 more source
Oral antigen exposure under costimulation blockade induces Treg cells to establish immune tolerance. [PDF]
Arai M +9 more
europepmc +1 more source

