Results 141 to 150 of about 4,329 (161)

Targeting FPR1 to prevent doxorubicin-induced cardiomyopathy

European Heart Journal Supplements
Abstract Background/Introduction Doxorubicin (DOX) is effective against cancer but can cause cardiotoxicity and immunosuppression, reducing its utility. Formyl peptide receptor-1 (FPR1) is essential for DOX-induced immunologic activation; however, a prevalent FPR1 variant (rs867228) diminishes this ...
L Schirone, D Vecchio, V Valenti, V Pezone, V Picchio, M Forte, S Sciarretta   +6 more
openaire   +1 more source

FPR1 Antagonist (BOC-MLF) Inhibits Amniotic Epithelial-mesenchymal Transition

Current Medical Science
Premature rupture of membranes (PROM) is a common pregnancy disorder that is closely associated with structural weakening of fetal membranes. Studies have found that formyl peptide receptor 1 (FPR1) activates inflammatory pathways and amniotic epithelialmesenchymal transition (EMT), stimulates collagen degradation, and leads to membrane weakening and ...
Xiao-Mei, Huang, E, Liao, Jun-Qun, Liao, Ya-Ling, Liu, Yong, Shao   +4 more
openaire   +2 more sources

Development of potent isoflavone-based formyl peptide receptor 1 (FPR1) antagonists and their effects in gastric cancer cell models

European Journal of Medicinal Chemistry, 2023
Mark Quinn, Marcello Leopoldo, Rosalba D'Alessandro   +2 more
exaly  

FPR1

AfCS-Nature Molecule Pages, 2006
openaire   +1 more source

Molecular Structure, Expression and Role of TAFA4 and its Receptor FPR1 in the Spinal Cord

Frontiers in Cell and Developmental Biology, 2022
Si-Pin Zhu, Samuel Bennett, Bennett Samuel   +2 more
exaly  

Polymorphism of formyl peptide receptor 1 (FPR1) reduces the therapeutic efficiency and antitumor immunity after neoadjuvant chemoradiotherapy (CCRT) treatment in locally advanced rectal cancer

Cancer Immunology, Immunotherapy, 2021
Tao-Wei Ke, Kevin Chih-Yang Huang, Shu-Fen Chiang   +2 more
exaly  

MODULATORS OF FPR1 AND METHODS OF USING THE SAME

2022
SHI FU-DONG, WANG YONGJUN, LIU QIANG, LI ZHIGUO, MA TIANWEI, HUANG ZHENG, SHI FENG   +6 more
openaire   +5 more sources

SIRT3 Regulates the ROS-FPR1/HIF-1α Axis under Hypoxic Conditions to Influence Lung Cancer Progression

Cell Biochemistry and Biophysics, 2023
exaly  

Evaluation of human leukocyte N-formylpeptide receptor (FPR1) SNPs in aggressive periodontitis patients

Genes and Immunity, 2003
Debora Pallos, Erhan Firatli, Eleanor Feingold   +2 more
exaly  

Synthesis and evaluation of FPR1 inhibitors as a novel treatment for cancers [1331]

2021
Aghamohammadi, Amin, Di Lu, , Salem, Anwar, Cooper, Patricia A, Shnyder, Steven D, Vinader, Victoria, Kamyar Afarinkia   +6 more
openaire   +1 more source