Results 91 to 100 of about 74,030 (274)

Fractional Calculus for Non-Discrete Signed Measures

Mathematics
In this paper, we suggest a first-ever construction of fractional integral and differential operators based on signed measures including a vector-valued case. The study focuses on constructing the fractional power of the Riemann–Stieltjes integral with a
Vassili N. Kolokoltsov, Elina L. Shishkina   +1 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

New Inequalities for GA–h Convex Functions via Generalized Fractional Integral Operators with Applications to Entropy and Mean Inequalities

Fractal and Fractional
We prove the inequalities of the weighted Hermite–Hadamard type the and Hermite–Hadamard–Mercer type for an extremely rich class of geometrically arithmetically-h-convex functions (GA-h-CFs) via generalized Hadamard–Fractional integral operators (HFIOs).
Asfand Fahad, Zammad Ali, Shigeru Furuichi, Saad Ihsan Butt, Ayesha, Yuanheng Wang   +5 more
doaj   +1 more source

Results on integral inequalities for a generalized fractional integral operator unifying two existing fractional integral operators

Nonlinear Analysis: Modelling and Control
The main aim of this article is to design a novel framework to study a generalized fractional integral operator that unifies two existing fractional integral operators. To ensure the suitable selection of the operator and with the discussion of special cases, it is shown that our considered fractional integral generalizes the well-known Atangana ...
Supriya Kumar Paul, Lakshmi Narayan Mishra, Vishnu Narayan Mishra   +2 more
openaire   +2 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

On boundedness of unified integral operators for quasiconvex functions

Advances in Difference Equations, 2020
This work deals with the bounds of a unified integral operator with which several fractional and conformable integral operators are directly associated. By using quasiconvex and monotone functions we establish bounds of these integral operators. We prove
Dongming Zhao, Ghulam Farid, Muhammad Zeb, Sohail Ahmad, Kahkashan Mahreen   +4 more
doaj   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

On the Behaviors of Rough Fractional Type Sublinear Operators on Vanishing Generalized Weighted Morrey Spaces

International Journal of Analysis and Applications, 2019
The aim of this paper is to get the boundedness of rough sublinear operators generated by fractional integral operators on vanishing generalized weighted Morrey spaces under generic size conditions which are satisfied by most of the operators in harmonic
Ferit Gurbuz
doaj   +2 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source