Results 131 to 140 of about 8,292 (268)

Immunomodulatory Effects of Rhaphidophora Korthalsii Methanol Extract on Natural Killer Cell Activation and Cytolytic Activity [PDF]

open access: yes, 2010
Rhaphidophora korthalsii (Araceae) is a root-climber plant which has been previously identified as splenocyte immunostimulator. The purpose of this study was to examine the in vitro and in vivo immunomodulatory effect of R.
Yeap, Swee Keong
core  

Advanced Corneal Hydrogels: From Passive Replacement to Active Regeneration and Intelligent Interaction

open access: yesAdvanced Science, EarlyView.
This review charts the evolution of corneal hydrogels from passive replacements to active and intelligent systems, evaluating natural and synthetic materials while addressing design challenges such as transparency and strength. Advanced applications such as scarless wound healing, three‐dimensional bioprinting, and smart wearables are highlighted to ...
Xinwei Wang   +9 more
wiley   +1 more source

Bioinspired Engineering of Streamlined Skeletal Interoception: Neural Bioprinted Piezoelectric Scaffolds for Neuro‐Vascularized Bone Regeneration

open access: yesAdvanced Science, EarlyView.
This study develops neural bioprinted piezoelectric scaffolds which construct local “sensor‐effector” circuit, inspired by the skeletal interoception system. Upon US stimulation sensing and mechanoelectrical coupling by PLLA nanofibers, the incorporated DRG neurons effect through Ca2+ influx‐induced enhanced secretion and expression of CGRP.
Yingze Su   +18 more
wiley   +1 more source

Dynamic Covalent Networks of Molecular Clusters for Hard and Impact‐Resistant Glass with Feasible Processability

open access: yesAdvanced Science, EarlyView.
Molecular granular material glass is fabricated by crosslinking sub‐nm POSS clusters with dynamic borate ester bonding while the materials combine high transparency, modulus, and hardness with superior impact resistance and (re)processability, offering a promising strategy for creating robust yet highly processable organic glasses.
Haiyan Xiao   +4 more
wiley   +1 more source

Therapeutic efficacy of a potent anti-Venezuelan equine encephalitis virus antibody is contingent on Fc effector function

open access: yesmAbs
The development of specific, safe, and potent monoclonal antibodies (Abs) has led to novel therapeutic options for infectious disease. In addition to preventing viral infection through neutralization, Abs can clear infected cells and induce ...
Jennifer L. Schwedler   +10 more
doaj   +1 more source

The Pharmacodynamic Functions of Low-Dose Rapamycin as a Model for Universal Influenza Protection [PDF]

open access: yes, 2017
One of the most sought after breakthroughs in modern influenza research is the creation of a universal influenza vaccine that would protect against all strains of avian influenza.
Gust, William
core   +1 more source

Ultrahigh‐Linear Bio‐Inspired Janus Elastomeric Strain Sensor with High Sensitivity and Stretchability via Surface Wrinkle Engineering

open access: yesAdvanced Science, EarlyView.
A bio‐inspired Micro‐wrinkled Janus elastomeric flexible strain sensor mimicking wrinkled‐leaf viburnum is developed. Endowed with a synergistic sensing mechanism including wrinkle‐guided microcracks, modulus‐gradient‐driven strain division, and a parallel conductive circuit, it achieves ultra‐high linearity, sensitivity, wide strain range, and ...
Jing Lin   +11 more
wiley   +1 more source

Beyond Cartilage‐Inspired Supramolecular Polyurethane for Adaptive Impact‐Resistant Protection with Robustness, Self‐Healing, and Recyclability

open access: yesAdvanced Science, EarlyView.
Cartilage‐inspired supramolecular polyurethane–urea (PU‐BAMB) elastomers are developed by integrating hierarchical hydrogen bonding and π–π stacking interactions within a dynamically reconfigurable network. This synergistic supramolecular architecture overcomes the intrinsic trade‐off between rigidity and recoverability, imparting exceptional toughness,
Rou‐Han Lai   +14 more
wiley   +1 more source

Structural characterization of human monoclonal antibodies targeting uncommon antigenic sites on spike glycoprotein of SARS-CoV

open access: yesThe Journal of Clinical Investigation
The function of the spike protein N terminal domain (NTD) in coronavirus (CoV) infections is poorly understood. However, some rare antibodies that target the SARS-CoV-2 NTD potently neutralize the virus.
Naveenchandra Suryadevara   +12 more
doaj   +1 more source

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