Results 161 to 170 of about 7,556 (242)

Mechanochemical Strategies Applied to the Late‐Stage Modifications of Pharmaceutically Active Compounds

open access: yesAngewandte Chemie International Edition, Accepted Article.
This review explores the potential of mechanochemistry in the late‐stage modification of active pharmaceutical ingredients (APIs), offering a comprehensive analysis of methods designed to transform structurally complex molecular scaffolds. By examining the scope, efficiency, and mechanistic aspects of these approaches, the review highlights protocols ...
Johanna Templ, Lars Borchardt
wiley   +1 more source

Successful treatment of dissecting cellulitis with certolizumab pegol in a pregnant patient. [PDF]

open access: yesJAAD Case Rep, 2023
Almuhanna N   +6 more
europepmc   +1 more source

A Monolithium Monohydrogen Porphyrin

open access: yesAngewandte Chemie International Edition, EarlyView.
A monohydrogen metalloporphyrin was synthesized by reacting lithium vapor with a thin film of tetraphenylporphyrin under UHV conditions. The resulting LiHTPP complex is thermally stable and isolable by vacuum sublimation. Spectroscopic and theoretical analyses reveal insights into its nonplanar structure, energetics, and mechanism of formation and ...
Maik Schöniger   +3 more
wiley   +1 more source

A novel <i>in vitro</i> serum stability assay for antibody therapeutics incorporating internal standards. [PDF]

open access: yesMAbs
Li Y   +7 more
europepmc   +1 more source

Rheumatoid factors revisited in the age of biologic therapy. [PDF]

open access: yesRheumatology (Oxford)
Avci AB, Feist E, Burmester GR.
europepmc   +1 more source

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