Results 81 to 90 of about 8,200 (248)

Astma ning selle ravi omalizumabiga: toime, ohutus ja kasutamine lastel [PDF]

open access: yes, 2017
Bronhiaalastma on maailmas üks levinumaid haigusi, millele endiselt otsitakse tõhusamaid ravimeid. Kliinilises praktikas üle kümne aasta kasutatud immunoglobuliin E vastase monokloonse antikeha omalizumabi toime põhimõte on teada, kuid vaja on täpsustada,
Lääts, Liis
core   +2 more sources

Block Copolymers: Emerging Building Blocks for Additive Manufacturing

open access: yesAdvanced Functional Materials, EarlyView.
This review addresses how block copolymer (BCP) physics and rheology have led to the widespread use of BCPs in advanced additive manufacturing techniques, with particular emphasis on the untapped potential of these nanostructured materials toward achieving multi‐scale architected materials with unique, programmable material properties.
Alice S. Fergerson   +3 more
wiley   +1 more source

Upcycling of Disposable Face Masks into Water‐Resistant and Flame Retardant Foams

open access: yesAdvanced Functional Materials, EarlyView.
Disposable mask waste is upcycled into lightweight polypropylene‐based foams with tunable porosity and composite architectures reinforced by ear‐loop fibers. The sustainable solvent‐based process enables upcycling rates of 91% and solvent recovery of >90%.
Jingjing Pan   +3 more
wiley   +1 more source

Generation and preclinical assessment of depemokimab, an enhanced IL-5 antagonist monoclonal antibody

open access: yesHeliyon
This study describes the affinity maturation, molecular engineering, and preclinical assessment of depemokimab, an enhanced anti-interleukin-5 antagonist antibody.
Martin Orecchia   +12 more
doaj   +1 more source

Expression of Colorectal Cancer Antigenic Protein Fused to IgM Fc in Chinese Cabbage (Brassica rapa)

open access: yesPlants, 2020
The epithelial cell adhesion molecule (EpCAM) is a tumor-associated antigen and a potential target for tumor vaccine. The EpCAM is a cell-surface glycoprotein highly expressed in colorectal carcinomas.
Ye-Rin Lee   +8 more
doaj   +1 more source

Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation [PDF]

open access: yes, 2017
Joint modeling of a number of phenotypes using multivariate methods has often been neglected in genome-wide association studies and if used, replication has not been sought. Modern omics technologies allow characterization of functional phenomena using a
Aulchenko, Yurii S.   +14 more
core   +4 more sources

Nano‐ and Micro‐Sized Solid Materials Used as Antiviral Agents

open access: yesAdvanced Functional Materials, EarlyView.
Due to the rise of viral infections in humans and possible viral outbreaks, the use of nano‐ or micro‐sized materials as antiviral agents is rapidly increasing. This review explores their antiviral properties against RNA and DNA viruses, either as a prevention or a treatment tool, by delving into their mechanisms of action and how to properly assess ...
Orfeas‐Evangelos Plastiras   +6 more
wiley   +1 more source

Novel Functional Materials via 3D Printing by Vat Photopolymerization

open access: yesAdvanced Functional Materials, EarlyView.
This Perspective systematically analyzes strategies for incorporating functionalities into 3D‐printed materials via Vat Photopolymerization (VP). It explores the spectrum of achievable functionalities in recently reported novel materials—such as conductive, energy‐storing, biodegradable, stimuli‐responsive, self‐healing, shape‐memory, biomaterials, and
Sergey S. Nechausov   +3 more
wiley   +1 more source

PCSK9 stimulates Syk, PKCδ, and NF-κB, leading to atherosclerosis progression independently of LDL receptor

open access: yesNature Communications
Proprotein convertase subtilisin/kexin type-9 (PCSK9) binds to and degrades low-density lipoprotein (LDL) receptor, leading to increase of LDL cholesterol in blood. Its blockers have emerged as promising therapeutics for cardiovascular diseases.
Dasom Shin   +16 more
doaj   +1 more source

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