Results 81 to 90 of about 8,292 (268)

Astma ning selle ravi omalizumabiga: toime, ohutus ja kasutamine lastel [PDF]

, 2017
Bronhiaalastma on maailmas üks levinumaid haigusi, millele endiselt otsitakse tõhusamaid ravimeid. Kliinilises praktikas üle kümne aasta kasutatud immunoglobuliin E vastase monokloonse antikeha omalizumabi toime põhimõte on teada, kuid vaja on täpsustada,
Lääts, Liis
core   +2 more sources

Science‐Towards‐Technology Breakthrough in CO2 Electroreduction: Multiphysics, Multiscale, and Artificial Intelligence Insights

Advanced Materials, EarlyView.
Electrochemical CO2RR is a key technology for converting CO2 into chemicals, but there remains a gap between “laboratory science” and “engineering practice” in current research. This review establishes a multi‐scale research framework, encompassing atomic‐level characterization, microenvironment regulation, external field‐assisted optimization, and AI ...
Ping Hong, Changfan Xu, Huaping Zhao, Yong Lei   +3 more
wiley   +1 more source

False Positive Drug Results by ELISA Associated with Enzymatic Hair Digestion [PDF]

, 2017
Following the experiment that have been designed for immunological screening test followed by a GC-MS confirmation method for the simultaneous analysis of delta-9-tetrahydrocannabinol (9-THC) , 11-nor-9-Carboxy-THC (THC-COOH), 11-Hydroxy-THC (OH-THC ...
Barker, James, Breidi, Salah, Naughton, Declan, Petroczi, Andrea   +3 more
core   +1 more source

Functional Metal Complexes for Solar–Light‐Driven Energy Conversion

Advanced Materials, EarlyView.
This review provides an exhaustive summary of the recent advancements of functional metal complexes in solar‐to‐electrical, ‐chemical, and ‐thermal energy conversion, comprising material categories, design strategies, underlying principles of operation, and identified improvement of performances.
Yanyan Qin, Dou Luo, Miao Zhang, Wai‐Yeung Wong   +3 more
wiley   +1 more source

De Rerum Natura: How Do Halide Perovskites Self‐Heal From Damage?

Advanced Materials, EarlyView.
How can lead‐halide‐perovskites self‐heal after damage from light, heat, mechanical strain, or radiation? We show that reversible chemical defects underly performance losses and recovery, highlighting the roles of halide and proton migration, redox‐driven reactions, and acid‐base equilibria.
Davide Raffaele Ceratti, Gary Hodes, David Cahen   +2 more
wiley   +1 more source

Generation and preclinical assessment of depemokimab, an enhanced IL-5 antagonist monoclonal antibody

Heliyon
This study describes the affinity maturation, molecular engineering, and preclinical assessment of depemokimab, an enhanced anti-interleukin-5 antagonist antibody.
Martin Orecchia, Katherine Welbeck, Jason Dexter, Laura Hook, Chika Akinseye, Marcin Kot, Alan Lewis, Don Somers, Tejinder Bhinder, Paul Hamblin, Sarah Elsey, David Willé, Steven Grant   +12 more
doaj   +1 more source

Glycosimilarity assessment of biotherapeutics 1: quantitative comparison of the N-glycosylation of the innovator and a biosimilar version of etanercept [PDF]

, 2018
K
Borza, Beáta, Guttman, András, Hajba, László, Szekrényes, Ákos, Szigeti, Márton   +4 more
core  

Hydrogelation via Supramolecular Copolymerization of Structural Water within Adaptive Metal–Organic Fibers

Advanced Materials, EarlyView.
Structural water is harnessed as an active co‐monomer to drive supramolecular polymerization in bulk water. Zinc(II) Salphen complexes confine water molecules to form hollow, metal–organic nanofibers that assemble into adaptive hydrogels with thermoresponsive mechanics and selective chiral recognition.
Merlin R. Stühler, Hesam Makki, Tarek Hilal, Debsena Chakraboty, Mathias Dimde, Kai Ludwig, Rainer Haag, Sabine Rosenfeldt, Dorothee Silbernagl, Andreas Schäfer, Alex J. Plajer   +10 more
wiley   +1 more source

Engineering of a recombinant fab antibody fragment against cortisol [PDF]

, 2013
The paper dwells upon the molecular cloning of genes coding the structure of mouse immunoglobulins, which can specifically bind steroid hormone cortisol.
Dormeshkin, D. O., Gilep, A. A., Ivashkevich, I. G., Leontiev, V. N.   +3 more
core  

Fc Engineering for Developing Therapeutic Bispecific Antibodies and Novel Scaffolds [PDF]

, 2017
Therapeutic monoclonal antibodies have become molecules of choice to treat autoimmune disorders, inflammatory diseases, and cancer. Moreover, bispecific/multispecific antibodies that target more than one antigen or epitope on a target cell or recruit ...
Abhishek Saxena, Donghui Wu, Hongyan Liu, Sachdev S. Sidhu   +3 more
core   +1 more source