Results 41 to 50 of about 261 (136)
Cell-free DNA fragmentomics in cancer
Cancer CellThe analysis of cell-free DNA (cfDNA) fragmentation patterns, known as "fragmentomics," has opened new opportunities in noninvasive cancer diagnostics. Due to its close relationships with genomic organization and cell death, cfDNA fragmentomics lies at the intersection of many aspects of cancer biology, including epigenetic dysregulation ...
W H Adrian, Tsui +2 more
openaire +2 more sources
International Journal of Cancer, Volume 158, Issue 10, Page 2771-2783, 15 May 2026.What's New? Circulating nuclear DNA (cir‐nDNA)‐based assessment of minimal residual disease (MRD) offers powerful post‐surgery prognostic insight for stage III colon cancer (CC). Sparse knowledge of post‐surgical variations and origins in cir‐nDNA, however, has limited its clinical application.
Andrei Kudriavtsev +17 more
wiley +1 more source
Disease Markers, Volume 2019, Issue 1, 2019., 2019 Although histologically benign, adamantinomatous craniopharyngioma (AC) pediatric brain tumor is a locally aggressive disease that frequently determines symptoms and hormonal dysfunctions related to the mass effect on the surrounding structures. Another typical feature of this benign neoplasm is the presence of voluminous liquid cysts frequently ...
Claudia Martelli +12 more
wiley +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, Volume 20, Issue 3, Page 588-610, March 2026.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Review of Small Gauge Vitrectomy: Progress and Innovations
Journal of Ophthalmology, Volume 2017, Issue 1, 2017., 2017 Purpose. To summarise the surgical advances and evolution of small gauge vitrectomy and discuss its principles and application in modern vitreoretinal surgery. The advent of microincisional vitrectomy systems (MIVS) has created a paradigm shift away from twenty‐gauge vitrectomy systems, which have been the gold standard in the surgical management of ...
Shaheeda Mohamed +3 more
wiley +1 more source
Exploring the Conformational Landscape of Bioactive Small Molecules [PDF]
, 2020 By using a combination of classical Hamiltonian replica exchange with high-level quantum mechanical calculations on more than one hundred drug-like molecules, we explored here the energy cost associated with binding of drug-like molecules to target ...
David Moreno +11 more
core +1 more source
Clinical Application of Peripheral Blood Biomarkers for Solid Tumors
MedComm, Volume 7, Issue 3, March 2026.Peripheral blood biomarkers provide a minimally invasive, dynamic, and potentially more accurate means to obtain a comprehensive tumor profile. Technologies for detecting them are advancing, and with the help of artificial intelligence, they are being used more and more often for cancer diagnosis, prognostic assessment, and therapeutic monitoring ...
Xinru Tu, Mengyan Tu, Junfen Xu
wiley +1 more source
Abstract Book for the 27th Congress of the European Hematology Association
, 2022 HemaSphere, Volume 6, Issue S3, Page 1-4130, June 2022.
wiley +1 more source
Cancer Science, Volume 116, Issue 1, Page 248-256, January 2025.We constructed a lung cancer detection model using four circulating free DNA (cfDNA) fragmentation features, and this model exhibits strong screening capabilities. It is not only effective for early cancer screening in asymptomatic individuals but also demonstrates robust detection capabilities in early cancer diagnosis.
Fudong Xu +9 more
wiley +1 more source