Results 131 to 140 of about 878 (143)

Prospective Evaluation of cfDNA Fragmentomes for Lung Cancer Detection

C99. ADVANCES IN BIOMARKERS ACROSS THE LUNG CANCER CONTINUUM, 2023
P.J. Mazzone, K.-K. Wong, J.J. Tsay, A. Vachani, A. Ryan, J. Carey, D. Jakubowski, K. Lumbard, J. Catallini, T. Maddala, P.B. Bach, R. Scharpf, N. Dracopoli, V. Velculescu   +13 more
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Abstract 3772: Leveraging the cfDNA fragmentome to predict immunotherapy response

Cancer Research
Abstract Background: Assessing immunotherapy response presents unique challenges, driven by the heterogeneity of clinical responses that are inadequately captured by conventional imaging. Early changes in circulating tumor DNA (ctDNA), captured by mutation-based next generation sequencing (NGS), have ...
Noushin Niknafs, Lavanya Sivapalan, Bahar Alipanahi, Daniel Rabizadeh, Mimi Najjar, Zachary L. Skidmore, Gavin Pereira, Caitlin Schonewolf, Bryan Chesnick, Peter Bach, Nicholas C. Dracopoli, Robert Scharpf, Joseph Murray, Victor Velculescu, Valsamo (Elsa) K. Anagnostou   +14 more
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Impact of Clinical Variables on cfDNA Fragmentomic Signatures and Their Potential as Confounders in Cancer Detection

Clinical Chemistry
Abstract Background Circulating cell-free DNA (cfDNA) fragmentomic features, such as fragment size and end motifs, have emerged as promising noninvasive biomarkers for cancer detection. However, the influence of nonmalignant clinical factors on these features remains unclear, potentially ...
Tae-Rim Lee, Eun Hye Cho, Jin Mo Ahn, Junnam Lee, Chang-Seok Ki, Byeong-Ho Jeong, Min-Jung Kwon, Eun-Hae Cho   +7 more
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Abstract 5884: Cancer subtype classification by cfDNA fragmentomics analysis

Cancer Research
Introduction: Nucleosome occupancy patterns at transcription factor binding sites (TFBS) exhibit differences between circulating tumor DNA (ctDNA) in cancer patients and normal plasma controls, as well as among different tumor subtypes.
Lisha Zhu, Chao Dai, Shuang Gan, Shidong Jia, Pan Du   +4 more
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Cell-Free DNA Fragmentomics: A Promising Biomarker for Diagnosis, Prognosis and Prediction of Response in Breast Cancer

International Journal of Molecular Sciences, 2022
Ugo De Giorgi, Michela Palleschi, Caterina Gianni   +2 more
exaly  

Blood has never been thicker: Cell-free DNA fragmentomics in the liquid biopsy toolbox of B-cell lymphomas

Seminars in Hematology, 2023
Leo Meriranta, Esa Pitkänen
exaly  

Sa1916 INTEGRATING FRAGMENTOMICS AND PROTEOMICS FOR EARLY DETECTION OF CHOLANGIOCARCINOMA

Gastroenterology
Vishruth Girish, Matthew A. Cooley, Caitlin J. VanLith, Adrianna Bartolomucci, Akshaya Annapragada, Daniel C. Bruhm, Sarah Short, Julia Velculescu, Sofia Velculescu, Shashikant Koul, Jillian Phallen, Lewis R. Roberts, Victor Velculescu, Robert B. Scharpf, Zachariah Foda   +14 more
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Fragmentomics of proteins and natural oligopeptides

Biophysics (Russian Federation), 2009
A A Zamyatnin, Zamyatnin A A
exaly  

Fragmentomics profiling and quantification of plasma Epstein-Barr virus DNA enhance prediction of future nasopharyngeal carcinoma

Cancer Cell
Wai Kei Jacky Lam, Brigette B Y, K C Allen Chan   +2 more
exaly  

Al'ternativnyi metod sinteza tetrakarbonovykh kislot s tsikloalifaticheskim fragmentom

From Chemistry Towards Technology Step-By-Step
Anastasia Firstova, Dmitry Ogorodnikov, Yulia Yusifova, Evgeny Kofanov, Anton Lebedev   +4 more
openaire   +1 more source