Results 61 to 70 of about 38,009 (292)

Francisella-like endosymbiont in Dermacentor reticulatus collected in Portugal [PDF]

, 2011
In Portugal, recent studies have confirmed the presence of Francisella tularensis in Dermacentor reticulatus. Bacterial endosymbionts with significant homology to F. tularensis have been described in several species of ticks.
Lopes de Carvalho, Isabel, Núncio, Maria Sofia, Santos, Nuno, Soares, Teresa, Zé-Zé, Líbia   +4 more
core   +1 more source

Francisella induced microparticulate caspase-1/gasdermin-D activation is regulated by NLRP3 independent of Pyrin.

PLoS ONE, 2018
Although the study of pathogen sensing by host defense systems continues to uncover a role for inflammasome components specific to particular pathogens, gaps remain in our knowledge.
Srabani Mitra, Erin Dolvin, Karthikeyan Krishnamurthy, Mark D Wewers, Anasuya Sarkar   +4 more
doaj   +1 more source

Construction of a New Phage Integration Vector pFIV-Val for Use in Different Francisella Species

Frontiers in Cellular and Infection Microbiology, 2018
We recently identified and described a putative prophage on the genomic island FhaGI-1 located within the genome of Francisella hispaniensis AS02-814 (F. tularensis subsp. novicida-like 3523).
Hana Tlapák, Kristin Köppen, Kerstin Rydzewski, Roland Grunow, Klaus Heuner   +4 more
doaj   +1 more source

Nlrp3 Increases the Host’s Susceptibility to Tularemia

Frontiers in Microbiology, 2021
Francisella tularensis (F. tularensis) is a Gram-negative, intracellular bacterium and the causative agent of a fatal human disease known as tularemia. The CDC has classified F.
Ragavan V. Suresh, Elizabeth W. Bradley, Matthew Higgs, Vincenzo C. Russo, Maha Alqahtani, Wiehua Huang, Chandra Shekhar Bakshi, Meenakshi Malik   +7 more
doaj   +1 more source

Yin and yang of interleukin-17 in host immunity to infection [version 1; referees: 2 approved] [PDF]

, 2017
The interleukin-17 (IL-17) family cytokines, such as IL-17A and IL-17F, play important protective roles in host immune response to a variety of infections such as bacterial, fungal, parasitic, and viral.
Das, Shibali, Khader, Shabaana
core   +3 more sources

Francisella novicida Two-Component System Response Regulator BfpR Modulates iglC Gene Expression, Antimicrobial Peptide Resistance, and Biofilm Production

Frontiers in Cellular and Infection Microbiology, 2020
Response regulators are a critical part of the two-component system of gene expression regulation in bacteria, transferring a signal from a sensor kinase into DNA binding activity resulting in alteration of gene expression. In this study, we investigated
S. Dean, M. Milton, J. Cavanagh, M. V. van Hoek   +3 more
semanticscholar   +1 more source

B-1 Cell Heterogeneity and the Regulation of Natural and Antigen-Induced IgM Production. [PDF]

, 2016
A small subset of B cells, termed B-1 cells, with developmental origins, phenotypes, and functions that are distinct from those of conventional B cells exist in mice. It contributes the vast majority of spontaneously produced "natural" IgM.
Alugupalli, Alugupalli, Ansel, Avrech, Barber, Baumgarth, Baumgarth, Baumgarth, Baumgarth, Ben-Hur, Berland, Boes, Boes, Briles, Cazac, Chace, Chen, Choi, Choi, Cole, Colombo, Cosenza, Cunningham, Dexter, Duber, Ehrenstein, Elvington, Flajnik, Forster, Fung, Gil-Cruz, Godin, Gordon, Ha, Haas, Hardy, Hardy, Hayakawa, Hayakawa, Holodick, Holodick, Holodick, Hooijkaas, Kantor, Kantor, Kawahara, Kearney, Kin, Kobayashi, Kretschmer, Kroese, Kroese, Lalor, Lalor, Lalor, Mercolino, Montecino-Rodriguez, Montecino-Rodriguez, Moon, Morris, Murakami, Nguyen, Nisitani, Ohdan, Okabe, Ouchida, Patel, Perdiguero, Rahyab, Reynolds, Sigal, Stoermann, Tominaga, Tornberg, van der Pol, Vas, Vaux, Waffarn, Wardemann, Watanabe, Yang, Yang, Yoshida, Yoshimoto, Yuan, Zhou   +85 more
core   +2 more sources

Genetic Sequence Matching Using D4M Big Data Approaches

, 2014
Recent technological advances in Next Generation Sequencing tools have led to increasing speeds of DNA sample collection, preparation, and sequencing. One instrument can produce over 600 Gb of genetic sequence data in a single run.
Dodson, Stephanie, Kepner, Jeremy, Ricke, Darrell O.   +2 more
core   +1 more source

Efficient targeted mutagenesis of rice and tobacco genomes using Cpf1 from Francisella novicida

Scientific Reports, 2016
CRISPR/Cas9 systems are nowadays applied extensively to effect genome editing in various organisms including plants. CRISPR from Prevotella and Francisella 1 (Cpf1) is a newly characterized RNA-guided endonuclease that has two distinct features as ...
A. Endo, Mikami Masafumi, H. Kaya, S. Toki   +3 more
semanticscholar   +1 more source

Francisella novicida pathogenicity island encoded proteins were secreted during infection of macrophage-like cells. [PDF]

PLoS ONE, 2014
Intracellular pathogens and other organisms have evolved mechanisms to exploit host cells for their life cycles. Virulence genes of some intracellular bacteria responsible for these mechanisms are located in pathogenicity islands, such as secretion ...
Rebekah F Hare, Karsten Hueffer
doaj   +1 more source