Results 91 to 100 of about 24,449 (253)

The European Union One Health 2024 Zoonoses Report

EFSA Journal, Volume 23, Issue 12, December 2025.
Abstract This report by the European Food Safety Authority and the European Centre for Disease Prevention and Control presents the results of zoonoses monitoring and surveillance activities carried out in 2024 in 27 Member States (MSs), the United Kingdom (Northern Ireland) and eight non‐MSs, according to the Zoonoses Directive 2003/99/EC.
European Food Safety Authority (EFSA) | European Centre for Disease Prevention and Control (ECDC)
wiley   +1 more source

Metapopulation structure for perpetuation of Francisella tularensis tularensis [PDF]

BMC Microbiology, 2009
AbstractBackgroundOutbreaks of Type A tularemia due toFrancisella tularensis tularensisare typically sporadic and unstable, greatly hindering identification of the determinants of perpetuation and human risk. Martha's Vineyard, Massachusetts has experienced an outbreak of Type A tularemia which has persisted for 9 years.
Telford Sam R, Saviet Benjamin, Goethert Heidi K   +2 more
openaire   +3 more sources

Azithromycin effectiveness against intracellular infections of Francisella

BMC Microbiology, 2010
Background Macrolide antibiotics are commonly administered for bacterial respiratory illnesses. Azithromycin (Az) is especially noted for extremely high intracellular concentrations achieved within macrophages which is far greater than the serum ...
Mann Barbara J, Qin Aiping, Hunter Lyman, Ahmad Saira, van Hoek Monique L   +4 more
doaj   +1 more source

Atg5-Deficient Mice Infected with Francisella tularensis LVS Demonstrate Increased Survival and Less Severe Pathology in Internal Organs

Microorganisms, 2020
Francisella tularensis is a highly virulent intracellular pathogen that proliferates within various cell types and can infect a multitude of animal species. Francisella escapes the phagosome rapidly after infection and reaches the host cell cytosol where
Ina Kelava, Mirna Mihelčić, Mateja Ožanič, Valentina Marečić, Maša Knežević, Marija Ćurlin, Sanja Štifter, Anders Sjöstedt, Marina Šantić   +8 more
doaj   +1 more source

Mucosal‐Associated Invariant T Cells: Origins, Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 6, Issue 11, November 2025.
Mucosa‐associated invariant T (MAIT) cells are an evolutionarily conserved class of innate‐like T lymphocytes that rely on MR1 molecules to recognize microbial metabolites and play a central role in immune surveillance and inflammatory regulation.
Cheng Zhu, Qian Huai, Yishan Du, Xingyu Li, Fumin Zhang, Yongkang Zhang, Mengwei Wu, Ying Dai, Xiaolei Li, Hanren Dai, Hua Wang   +10 more
wiley   +1 more source

Galleria mellonella Reveals Niche Differences Between Highly Pathogenic and Closely Related Strains of Francisella spp.

Frontiers in Cellular and Infection Microbiology, 2018
Francisella tularensis, a highly virulent bacteria that causes the zoonotic disease tularemia, is considered a potential agent of biological warfare and bioterrorism.
Johanna Thelaus, Eva Lundmark, Petter Lindgren, Andreas Sjödin, Mats Forsman   +4 more
doaj   +1 more source

Glycoproteomics and Its Role in Understanding Bacterial O‐Linked Glycosylation

PROTEOMICS, Volume 25, Issue 21-22, Page 160-176, November 2025.
ABSTRACT Protein glycosylation is now recognized as a ubiquitous process observed in all domains of life. Within bacterial species, carbohydrates can be attached to multiple residues with glycosylation of serine, threonine, or tyrosine residues via their hydroxyl side chains referred to as O‐linked glycosylation.
Kristian I. Karlic, Hamza Tahir, Nichollas E. Scott   +2 more
wiley   +1 more source

Identification of Francisella novicida mutants that fail to induce prostaglandin E2 synthesis by infected macrophages.

Frontiers in Microbiology, 2013
Francisella tularensis is the causative agent of tularemia. We have previously shown that infection with F. tularensis Live Vaccine Strain (LVS) induces macrophages to synthesize prostaglandin E2 (PGE2). Synthesis of PGE2 by F.
Matthew Dale Woolard, Lydia M Barrigan, Lydia M Barrigan, James R Fuller, Adam S Buntzman, Joshua eBryan, Colin eManoil, Tom eKawula, Jeffrey A Frelinger   +8 more
doaj   +1 more source

Genetic identification of unique immunological responses in mice infected with virulent and attenuated Francisella tularensis [PDF]

, 2011
Francisella tularensis is a category A select agent based on its infectivity and virulence but disease mechanisms in infection remain poorly understood. Murine pulmonary models of infection were therefore employed to assess and compare dissemination and ...
Alan R. Schenkel, Andersson, Andersson, Andersson, Benoit, Bosio, Bosio, Butchar, Chase, Chiavolini, Chocarro, Cole, Conlan, Cremer, Dennis, Dennis, Edwin, Eisen, Elkins, England, Fortier, Gonzalez-Juarrero, Han, Helle Bielefeldt-Ohmann, Huang da, Jia, Keim, Lennon-Duménil, Liu, Luhrmann, Luke C. Kingry, Mahawar, Metzger, Moe, Ng, Nicole L. Marlenee, Ortaldo, Pechous, Petersen, Qin, Richard A. Bowen, Richard A. Slayden, Ryan M. Troyer, Sawyer, Sjostedt, Steven W. Dow, Troyer, Twine, Twine, Voth, Westgaard, Wilson, Woolard, Woolard   +53 more
core   +1 more source

Ecology ofFrancisella tularensis

Annual Review of Entomology, 2020
Tularemia is a Holarctic zoonosis caused by the gamma proteobacterium Francisella tularensis and is considered to be a vector-borne disease. In many regions, human risk is associated with the bites of flies, mosquitoes, or ticks. But the biology of the agent is such that risk may be fomite related, and large outbreaks can occur due to inhalation or ...
Sam R, Telford, Heidi K, Goethert
openaire   +3 more sources