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Frataxin: from the sequence to the biological role
Biophysical ReviewsFrataxin is a small protein involved in the rare disease Friedreich's ataxia. During the last few years, significant knowledge has been gained concerning frataxin folding, structure, dynamics, and function. In eukaryotic organisms, it is located in the mitochondrial matrix, and recently, its macromolecular context was revealed.
Pignataro, María Florencia +4 more
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Frataxin controls ketone body metabolism through regulation of OXCT1
PNAS Nexus, 2022Yi Na Dong, Peining Xu, Nathan Warren
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METHODS OF QUANTIFYING FRATAXIN AND FRATAXIN FUSION PROTEINS
2021BETTOUN JOAN DAVID +4 more
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Iron‐induced oligomerization of yeast frataxin homologue Yfh1 is dispensable in vivo
EMBO Reports, 2004Kerman Aloria, Elizabeth A Craig
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High Levels of Frataxin Overexpression Lead to Mitochondrial and Cardiac Toxicity in Mouse Models
Molecular Therapy - Methods and Clinical Development, 2020Helene Puccio, Laurence Reutenauer
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Frataxin participates to the hypoxia-induced response in tumors
Cell Death and Disease, 2011Ivano Condò +2 more
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