Results 11 to 20 of about 333,221 (246)

Clinical heterogeneity in a family with flail arm syndrome and review of hnRNPA1‐related spectrum

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1910-1917, December 2022., 2022
Abstract Objective Flail arm syndrome (FAS) is one of the atypical subtypes of amyotrophic lateral sclerosis (ALS). Mutations in hnRNPA1 encoding heterogeneous nuclear ribonucleoprotein (hnRNP) A1 are a rare genetic cause of ALS. Herein, marked clinical heterogeneity of FAS in a pedigree with a known hnRNPA1 variant was described to raise early ...
Xiaochen Han, Feixia Zhan, Yuxin Yao, Li Cao, Jianguo Liu, Sheng Yao   +5 more
wiley   +1 more source

The clinical spectrum of SMA‐PME and in vitro normalization of its cellular ceramide profile

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1941-1952, December 2022., 2022
Abstract Objective The objectives of this study were to define the clinical and biochemical spectrum of spinal muscular atrophy with progressive myoclonic epilepsy (SMA‐PME) and to determine if aberrant cellular ceramide accumulation could be normalized by enzyme replacement.
Michelle M. Lee, Graeme S. V. McDowell, Darryl C. De Vivo, Daniel Friedman, Samuel F. Berkovic, Maria Spanou, Argirios Dinopoulos, Katheryn Grand, Pedro A. Sanchez‐Lara, Michelle Allen‐Sharpley, Jodi Warman‐Chardon, Alexander Solyom, Thierry Levade, Edward H. Schuchman, Steffany A. L. Bennett, David A. Dyment, Toni S. Pearson   +16 more
wiley   +1 more source

Biochemical changes associated with the fermentation of baobab seeds in Maari: An alkaline fermented seeds condiment from western Africa

Journal of Ethnic Foods, 2015
Chemical changes during the fermentation of baobab seeds for production of Maari, a food condiment used in West Africa, were studied. Results showed a wide variety of free amino acids including essential amino acids in the unfermented seeds. Fermentation
Charles Parkouda, Fatoumata Ba/Hama, Laurencia Ouattara/Songre, Kwaku Tano-Debrah, Bréhima Diawara   +4 more
doaj   +1 more source

Topicality of identification of free fatty acids pattern in biologic substrates in the diagnosis of gastroenterological diseases

Gastroenterologìa, 2017
The article shows the role of free fatty acids in the pathogenesis of metabolic and gastroenterological disorders. An expediency of gas chromatography method for determination of free fatty acids pattern in biologic samples (blood serum, urine, feces and
V.I. Didenko, I.A. Klenina, S.O. Babii, V.A. Karachynova   +3 more
doaj   +1 more source

Plasma Levels of Free Fatty Acids in Women with Gestational Diabetes and Its Intrinsic and Extrinsic Determinants: Systematic Review and Meta-Analysis

Journal of Diabetes Research, 2019
Background. Free fatty acids, also known as nonesterified fatty acids, are proinflammatory molecules that induce insulin resistance in nonpregnant individuals.
Jose Rafael Villafan-Bernal, Mariana Acevedo-Alba, Rodrigo Reyes-Pavon, Guillermo Andres Diaz-Parra, Diana Lucia Lip-Sosa, Hilda Imelda Vazquez-Delfin, Martha Hernandez-Muñoz, Daniel Ely Bravo-Aguirre, Francesc Figueras, Raigam Jafet Martinez-Portilla   +9 more
doaj   +1 more source

Study of the Royal Jelly Free Fatty Acids by Liquid Chromatography-High Resolution Mass Spectrometry (LC-HRMS)

Metabolites, 2020
The lipidome of royal jelly (RJ) consists of medium-chained (8−12 carbon atoms) free fatty acids. We present herein a liquid chromatography-high resolution mass spectrometry (HRMS) method that permits the determination of RJ fatty acids and at the ...
Maroula G. Kokotou, Christiana Mantzourani, Rodalia Babaiti, George Kokotos   +3 more
doaj   +1 more source

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

FEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali, Gloria Giacomello, Michela Vuono, Silvia Gregori   +3 more
wiley   +1 more source

THE EFFECT OF HEMP PRЕSS CAKE FLOUR ON FATTY ACIDS COMPOSITION AND MICROBIOLOGICAL QUALITY OF GLUTEN FREE BREAD

Scientific Study & Research: Chemistry & Chemical Engineering, Biotechnology, Food Industry
The aim of this paper is to determine the impact of hemp press cake flour (HPCF) on fatty acids and the microbiological quality of gluten-free bread. Seven types of gluten-free bread with different amounts of HPCF (0, 5, 10, 15, 20, 25 and 30 %) were ...
GJORE NAKOV , NATALIJA ATANASOVA-PANCEVSKA, SILVIYA IVANOVA , MARIA NIKOLOVA , IVAN DIMOV , MARKO JUKIĆ , JASMINA LUKINAC   +6 more
doaj   +1 more source

Study of the lipidic fraction of the artisanal blue cheeses from the Principado de Asturias

Grasas y Aceites, 1994
A study concerning the lipidic fraction in relation to esterified fatty acids composition, free fatty acids contents, triglyceride analysis and gross composition characteristics from artisanal blue cheeses made in the Principado de Asturias was carried ...
L. Alonso, C. Antuña, M. I. Pardo
doaj   +1 more source

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

FEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga, Kazuki Harada, Takuya Yamauchi, Tetsuya Kitaguchi, Masami Yokota Hirai, Mitsuharu Matsumoto, Takashi Tsuboi   +6 more
wiley   +1 more source