Results 181 to 190 of about 440,342 (269)

Carbon dot nanozymes as free radical scavengers for the management of hepatic ischemia-reperfusion injury by regulating the liver inflammatory network and inhibiting apoptosis. [PDF]

J Nanobiotechnology
Geng H, Chen J, Tu K, Tuo H, Wu Q, Guo J, Zhu Q, Zhang Z, Zhang Y, Huang D, Zhang M, Xu Q.   +11 more
europepmc   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Free radicals and diseases.

Nihon Naika Gakkai Zasshi, 1992
openaire   +3 more sources

Targeting engineered cell membrane camouflaged gallic acid-cerium nanozyme for intercepting the inflammation-free radical vicious cycle in atherosclerosis. [PDF]

J Nanobiotechnology
Han Z, Chen Q, Duan X, He Z, Mou N, Cao Y, Ou Y, He H, Zhang C, Yang X, Qu K, Zhang K, Malashicheva A, Zhong Y, Li C, Fu L, Wang G, Wu W.   +17 more
europepmc   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Free radical inhibition and total phenolic content in <i>Fomitopsis betulina</i> mycelium extract under different cultivation conditions. [PDF]

Front Fungal Biol
Zaichenko T, Barshteyn V, Sevindik M, Krupodorova T.   +3 more
europepmc   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Evaluation of free radical scavenging and anxiolytic activities of <i>Bunium persicum</i> (Boiss.) B. Fedtsch. bioactive metabolites through multi-method experimental and computational approaches. [PDF]

Front Pharmacol
Gani R, Yousuf U, Siddiquee NH, Mir MA, Yaseen A, Bashir N, Varadharajan V, Hossain MI, Dar PA, Dar MY, Bhat ZA, Bhat BA.   +11 more
europepmc   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Effects of Resveratrol-Loaded Nanoparticles on Follicular Survival, Stromal Integrity and Activity of Endogenous Free-Radical Scavengers in Bovine Ovarian Cortical Slices Cultured In Vitro. [PDF]

Reprod Domest Anim
Catunda MBA, Costa FDC, Bezerra VS, Caetano Filho FF, Ribeiro RP, Silva AA, Martins SD, Araújo VR, Reis AVF, Eloy JO, Silva JRV.   +10 more
europepmc   +1 more source