Results 91 to 100 of about 3,933,717 (303)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Free radicals and aging I. [PDF]

open access: yes, 2009
Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Biochemical Sciences Candidate: Pavla Brtnická Consultant: prof. RNDr. Eva Kvasničková, CSc Title: Free radicals and aging I.
Brtnická, Pavla
core   +1 more source

Free radicals, mitochondria, and hypoxia-ischemia in the developing brain

open access: yes, 2006
The immature brain is particularly susceptible to free radical injury because of its poorly developed scavenging systems and high availability of iron for the catalytic formation of free radicals.
Hagberg, Henrik,, Blomgren, Klas,
core  

Free radicals: Our enemies or friends ? [PDF]

open access: yes, 2007
Free radicals are atoms or groups of atoms containing at least one unpaired electron in their orbitals and can be formed when oxygen interacts with certain molecules.
Pala, Funda Sibel   +1 more
core  

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Analiza składu i właściwości mieszanek ziołowych dodawanych do produktów spożywczych typu instant

open access: yesHerbalism
Świat nieustannie pędzi do przodu, a my mamy coraz mniej czasu na codzienne czynności, dlatego coraz większą popularność zyskuje „kultura typu instant”. Samo słowo instant oznacza „zaraz”, „szybko”, „od razu”.
Aleksandra Baran   +2 more
doaj   +1 more source

Spin trapping as tool for investigating radiation induced free radicals in biologically active molecules

open access: yes, 2017
Since from the second half of the last century the spin trapping has found wide applications in chemistry, biology and medicine [1]. Of particular interest are the studied of the free radicals induced in biologically active molecules, such as DNA and ...
LONGO, Anna   +4 more
core  

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Editorial: Fruit ripening: From present knowledge to future development, Volume II

open access: yesFrontiers in Plant Science, 2022
José M. Palma   +2 more
doaj   +1 more source

Plant H2S and Transcription Factors (TFs) Interactions: Unexplored Area

open access: yesFrontiers in Bioscience-Landmark
Plant hydrogen sulfide (H2S) metabolism has garnered noteworthy attention due to its role in regulating many plant processes. The primary mechanism by which H2S exerts its signaling functions is through its reversible interaction with thiol groups on ...
Francisco J Corpas
doaj   +1 more source

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