Results 261 to 270 of about 320,731 (312)
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Molecular and Cellular Biochemistry, 1988
Aging is the progressive accumulation of changes with time that are responsible for the ever-increasing likelihood of disease and death. These irreversible changes are attributed to the aging process. This process is now the major cause of death in the developed countries. This fact is obscured by the protean nature of the contributions of this process
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Aging is the progressive accumulation of changes with time that are responsible for the ever-increasing likelihood of disease and death. These irreversible changes are attributed to the aging process. This process is now the major cause of death in the developed countries. This fact is obscured by the protean nature of the contributions of this process
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Archives of Biochemistry and Biophysics, 2002
Free radicals and reactive oxygen species (ROS) have been associated with the etiology and/or progression of a number of diseases and in aging. Many of the proteins oxidatively modified by free radicals contain side-chain carbonyl derivatives, which can be used as markers for protein oxidation.
Jackob, Moskovitz +2 more
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Free radicals and reactive oxygen species (ROS) have been associated with the etiology and/or progression of a number of diseases and in aging. Many of the proteins oxidatively modified by free radicals contain side-chain carbonyl derivatives, which can be used as markers for protein oxidation.
Jackob, Moskovitz +2 more
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Free Radical Biology and Medicine, 2013
Unlike bigger and more advanced animals, Caenorhabditis elegans does not generate NO, yet it was recently found that NO produced by chemical or biological sources exerts profound effects in that animal, leading to increased life span and thermotolerance. The biological source was Bacillus subtilis, a natural food for C. elegans.
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Unlike bigger and more advanced animals, Caenorhabditis elegans does not generate NO, yet it was recently found that NO produced by chemical or biological sources exerts profound effects in that animal, leading to increased life span and thermotolerance. The biological source was Bacillus subtilis, a natural food for C. elegans.
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The wanderings of a free radical
Free Radical Biology and Medicine, 2009In my career I have moved from chemistry to biochemistry to plant science to clinical chemistry and back again (in a partial way) to plants. This review presents a brief history of my research achievements (ascorbate-glutathione cycle, role of iron in oxidative damage and human disease, biomarkers of free radical damage, and studies on atherosclerosis ...
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Free Radical Biology and Medicine, 1988
The role of active oxygen species in diabetes is discussed in this review. Type I diabetes is caused by destruction of the pancreatic beta cells responsible for producing insulin. In humans, the diabetogenic process appears to be caused by immune destruction of the beta cells; part of this process is apparently mediated by white cell production of ...
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The role of active oxygen species in diabetes is discussed in this review. Type I diabetes is caused by destruction of the pancreatic beta cells responsible for producing insulin. In humans, the diabetogenic process appears to be caused by immune destruction of the beta cells; part of this process is apparently mediated by white cell production of ...
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Nature Chemistry, 2013
Thomas Tidwell reflects on the overlooked — but prescient — proposal by the British chemists Arthur Downes and Thomas Blunt for photochemical free-radical formation, decades before Moses Gomberg launched the field of radical chemistry by preparing triphenylmethyl, the first stable organic radical.
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Thomas Tidwell reflects on the overlooked — but prescient — proposal by the British chemists Arthur Downes and Thomas Blunt for photochemical free-radical formation, decades before Moses Gomberg launched the field of radical chemistry by preparing triphenylmethyl, the first stable organic radical.
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The British Journal of Radiology, 2001
Mention medical imaging and most radiologists and medical physicists will think of CT, MRI, ultrasound and nuclear medicine, the techniques that form the backbone of diagnostic radiology. Nevertheless, there are a number of other methods currently under development that are potentially capable of producing extremely valuable functional information. One
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Mention medical imaging and most radiologists and medical physicists will think of CT, MRI, ultrasound and nuclear medicine, the techniques that form the backbone of diagnostic radiology. Nevertheless, there are a number of other methods currently under development that are potentially capable of producing extremely valuable functional information. One
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Endometriosis and Free Radicals
Gynecologic and Obstetric Investigation, 1999Recent studies have shown that synthase for nitric oxide or scavenger enzymes is distributed throughout the endometrium. We have reported that endothelial nitric oxide synthase, originally identified in vascular endothelial cells, is distributed in glandular epithelial cells in the endometrium, peaking in the midsecretory phase.
H, Ota +3 more
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1977
A free-radical reaction is a chemical process in which molecules having unpaired electrons are involved. The radical species could be a starting compound or a product, but in organic chemistry, the most common cases are reactions that involve radicals as intermediates.
Francis A. Carey, Richard J. Sundberg
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A free-radical reaction is a chemical process in which molecules having unpaired electrons are involved. The radical species could be a starting compound or a product, but in organic chemistry, the most common cases are reactions that involve radicals as intermediates.
Francis A. Carey, Richard J. Sundberg
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Biochemical and Molecular Medicine, 1996
Free radicals that appear during physiological processes may lead to apoptosis in some pathological conditions when antioxidant capacity of the tissue is surpassed. Additionally, free radicals are involved in the control of apoptosis; antioxidant agents suppress apoptosis induced by a variety of stimuli.
I, Stoian, A, Oros, E, Moldoveanu
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Free radicals that appear during physiological processes may lead to apoptosis in some pathological conditions when antioxidant capacity of the tissue is surpassed. Additionally, free radicals are involved in the control of apoptosis; antioxidant agents suppress apoptosis induced by a variety of stimuli.
I, Stoian, A, Oros, E, Moldoveanu
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