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Free radical paradoxes

Free Radical Biology and Medicine, 2013
Unlike bigger and more advanced animals, Caenorhabditis elegans does not generate NO, yet it was recently found that NO produced by chemical or biological sources exerts profound effects in that animal, leading to increased life span and thermotolerance. The biological source was Bacillus subtilis, a natural food for C. elegans.
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Endometriosis and Free Radicals

Gynecologic and Obstetric Investigation, 1999
Recent studies have shown that synthase for nitric oxide or scavenger enzymes is distributed throughout the endometrium. We have reported that endothelial nitric oxide synthase, originally identified in vascular endothelial cells, is distributed in glandular epithelial cells in the endometrium, peaking in the midsecretory phase.
H, Ota   +3 more
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Free radical imaging

The British Journal of Radiology, 2001
Mention medical imaging and most radiologists and medical physicists will think of CT, MRI, ultrasound and nuclear medicine, the techniques that form the backbone of diagnostic radiology. Nevertheless, there are a number of other methods currently under development that are potentially capable of producing extremely valuable functional information. One
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Free radicals and aging

Trends in Neurosciences, 2004
Aging is characterized by decrements in maximum function and accumulation of mitochondrial DNA mutations, which are best observed in organs such as the brain that contain post-mitotic cells. Oxygen radicals are increasingly considered responsible for part of these aging changes.
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Free Radicals and Carcinogenesis

Free Radical Research Communications, 1990
The role of free radicals and active states of oxygen in human cancer is as yet unresolved. Various lines of evidence provide strong but inferential evidence that free radical reactions can be of crucial importance in certain carcinogenic mechanisms. A central point in considering free radical reactions in carcinogenesis is that human cancer is really ...
B D, Goldstein, G, Witz
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Modulation of platelet function by free radicals and free-radical scavengers

Trends in Pharmacological Sciences, 1993
Platelets have the capacity to generate oxygen-derived free radicals and are often present at inflammatory foci with other free-radical-generating cells such as white blood cells. Free radicals can modify platelet adhesion and aggregation directly or through effects on the vascular endothelium, which generates prostacyclin and nitric oxide.
D, Salvemini, R, Botting
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The need for a ?free radical initiative'

Diabetologia, 1996
The article presented by Drs. Paolisso and Giugliano discusses the possible relationship between oxidative stress and insulin action. The hypothesis formulated by the authors is that oxidative stress can impair insulin action through a change in the physical state of the plasma membrane of target cells, an increase in intracellular calcium content and ...
COMINACINI, Luciano   +2 more
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Free Radicals in Disease

Seminars in Reproductive Medicine, 1998
Partial reduction of molecular oxygen can generate reactive oxygen species (ROS), including the hydrogen peroxide, and the free radicals superoxide and hydroxyl. The formation of ROS is a feature of many degenerative diseases, such as atherosclerosis and neurodegeneration, Organisms contain a battery of defense mechanisms to prevent the formation of ...
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Photoionization of Free Radicals

International Journal of Radiation Applications and Instrumentation. Part C. Radiation Physics and Chemistry, 1974
Since this is the first lecture at this Institute on photoionization and free radicals, permit me to take a few minutes to outline my concept of these terms.
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The Significance of Free Radicals and Free Radical Scavengers in L1210 Leukemia

1988
L1210 leukemia is a murine leukemia which is associated with anemia and marked neutrophilia. In order to determine the significance of free radicals (FR) in this disorder, we determined the presence and localization of free radical scavengers (FRS) and scavenger-like systems in L1210 leukemia cells obtained in vivo and from in vitro cultures.
A C, Brown, J D, Lutton
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