Results 261 to 270 of about 317,834 (310)
Some of the next articles are maybe not open access.
2002
Given the increasing importance of reducing development time for new pharmaceutical products, formulation and process development scientists must continually look for ways to "work smarter, not harder." Within the product development arena, this means reducing the amount of trial and error empiricism in arriving at a formulation and identification of ...
Steven L, Nail +3 more
openaire +2 more sources
Given the increasing importance of reducing development time for new pharmaceutical products, formulation and process development scientists must continually look for ways to "work smarter, not harder." Within the product development arena, this means reducing the amount of trial and error empiricism in arriving at a formulation and identification of ...
Steven L, Nail +3 more
openaire +2 more sources
The Principles of Freeze-Drying
2014This chapter provides an up-to-date overview of freeze-drying (lyophilization) with particular relevance to stabilizing live cells or viruses for industrial applications as vaccines or seed culture. The chapter discusses the importance of formulation, cycle development, validation, and the need to satisfy pharmaceutical regulatory requirements ...
Gerald D J, Adams +2 more
openaire +2 more sources
Proceedings of the Royal Society of London. Series B. Biological Sciences, 1975
Abstract Most biological substances are unstable during storage owing to their high water content. This is why numerous attempts have been made over the last 100 years to prevent, by low temperature freezing, metabolic and biochemical degradations.
openaire +2 more sources
Abstract Most biological substances are unstable during storage owing to their high water content. This is why numerous attempts have been made over the last 100 years to prevent, by low temperature freezing, metabolic and biochemical degradations.
openaire +2 more sources
The Principles of Freeze-Drying
2007This chapter provides an up-to-date overview of freeze-drying (lyophilization) with particulars relevance to stabilizing live cells or viruses for industrial applications as vaccines or seed culture. The chapter discusses the importance of formulation, cycle development, validation, and the need to satisfy pharmaceutical regulatory requirements ...
openaire +2 more sources
Freeze Drying of Pharmaceuticals
2013Freeze-drying is a key step in many pharmaceutical manufacturing processes, as it provides long-term stability to formulations containing an active pharmaceutical ingredient. This entry first addresses the problem of formulations and various phases of a freeze-drying process, namely freezing, primary and secondary drying.
openaire +2 more sources
Freeze Drying and Microwave Freeze Drying as Encapsulation Methods
2017Encapsulation is used to protect sensitive materials from adverse environmental conditions and control their release during transportation, storage, and consumption. It is applied in various industrial sectors, such as food, nutraceutical, and pharmaceutical industries.
openaire +1 more source
Freeze-drying of Certain Viruses
Nature, 1965IT is important that a virus reference laboratory be able to hold viruses in the infectious state for long periods and to transmit them long distances. We have experienced difficulty with some newly isolated viruses of the respiratory tract. Some preparations of para-influenza viruses and rhinoviruses have become non-infectious after being frozen at ...
D A, TYRRELL, B, RIDGWELL
openaire +2 more sources
Cryopreservation and Freeze-Drying of Fungi Employing Centrifugal and Shelf Freeze-Drying
2007The aim of preserving a fungus is to maintain it in a viable state without change to its genetic, physiological, or anatomical characters. There are numerous methodologies available to preserve a fungus, but the two methods widely used by culture collections (biological or genetic resource centers) to achieve successful preservation are ...
Matthew J, Ryan, David, Smith
openaire +2 more sources
Freeze-Drying of Mammalian Sperm
2014Long-term preservation of mammalian sperm at suprazero temperatures is desired to save storage and space costs as well as to facilitate transport of preserved samples. This can be accomplished by the freeze-drying of sperm samples. Although freeze-drying results in immotile and membrane-compromised sperm, intracytoplasmic sperm injection (ICSI) can be ...
Levent, Keskintepe, Ali, Eroglu
openaire +2 more sources
A-to-Z Guide to Thermodynamics, Heat and Mass Transfer, and Fluids Engineering, 2006
Roberto Bruttini, Athanasios Liapis
+4 more sources
Roberto Bruttini, Athanasios Liapis
+4 more sources