Results 41 to 50 of about 229,386 (310)

The Effects of Freeze-Drying on the Strength Characteristics of Naturally Aged Book Papers [PDF]

open access: yes, 1981
Libraries occasionally have water main breaks, fires and floods. These disasters cause considerable water damage to thousands of books. Books that are left wet on the shelves will grow mold.
Sarokin, Steven D.
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Effects of Different Drying Methods on Physicochemical Properties and Nutritional Quality of Abalone Bioactive Peptides

open access: yesMolecules
This study conducted a systematic comparison of four drying methods (vacuum freeze-drying, spray drying, spray freeze-drying, and hot air drying) on abalone bioactive peptides, investigating their effects on physicochemical properties and nutritional ...
Qiting Li   +9 more
doaj   +1 more source

Preservation of flavor in freeze dried green beans [PDF]

open access: yes, 1973
Before freeze drying, green beans are heated to point at which their cell structure is altered. Beans freeze dried with altered cell structure have improved rehydration properties and retain color, flavor, and ...
Davis, D.   +2 more
core   +1 more source

Influence of the drying method in the antioxidant potential and chemical composition of four shrubby flowering plants from the tribe Genisteae (Fabaceae). [PDF]

open access: yes, 2011
Flowers from several common Mediterranean shrubs, such as those from the Cytisus genus and Genista genus (tribe Genisteae/Fabaceae) have long been used for medicinal purposes and seasoning in the northeastern Portuguese region.
Barros, Lillian   +3 more
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Drying technologies for messenger RNA and other nucleic acid-lipid nanoparticles: advances in freeze-drying and beyond

open access: yesAAPS Open
Nucleic acid therapeutics have emerged as the third major class of therapeutics, following small molecules and antibodies. Lipid nanoparticles (LNPs) serve as the leading platform for nucleic acid delivery.
Zixuan Zhen   +4 more
doaj   +1 more source

Physicochemical, bioactive compounds and antioxidant activities of sweet red corn under different drying methods

open access: yesNotulae Botanicae Horti Agrobotanici Cluj-Napoca, 2023
This study investigated the physicochemical properties, bioactive compounds, and antioxidant activities of sweet red corn under different drying methods.
Onanong PHUSEERIT   +1 more
doaj   +1 more source

Effects of freeze-drying on cytology, ultrastructure, DNA fragmentation, and fertilizing ability of bovine sperm [PDF]

open access: yes, 2007
Freeze-drying sperm is an alternative to cryopreservation. Although sperm from various species has been freeze-dried, there are few reports for bovine sperm.
Báo, Sônia Nair   +4 more
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

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